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Table 3 Analysis of endpoints

From: A clinical study of pegylated recombinant human granulocyte colony stimulating factor (PEG-rhG-CSF) in preventing neutropenia during concurrent chemoradiotherapy of cervical cancer

Endpoints

Experimental group (N = 40)

Control group (N = 18)

Statistics

P

Whether grade 3/4 neutropenia occurs

  

χ2 = 26.64

< 0.001

 Yes

4 (10.00%)

14 (77.78%)

  

 No

36 (90.00%)

4 (22.22%)

  

The duration of grade 3–4 neutropenia a

  

Z = 0.16

0.871

 n

4

14

  

 Median (Q1,Q3)

3.5 (3.0,4.5)

3.5 (3.0,9.0)

  

Whether grade 4 neutropenia occurs

  

χ2 = 4.50

0.034

 Yes

3 (7.50%)

6 (33.33%)

  

 No

37 (92.50%)

12 (66.67%)

  

Whether FN occurs

   

0.026

 Yes

0

3 (16.67%)

  

 No

40 (100.00%)

15 (83.33%)

  

Whether chemotherapy is delayed

  

χ2 = 12.35

< 0.001

 Yes

5 (12.50%)

11 (61.11%)

  

 No

35 (87.50%)

7 (38.89%)

  

Prolonged time of chemotherapy b

  

Z = 1.94

0.052

 n

5

11

  

 Median (Q1,Q3)

4.0 (3.0,6.0)

9.0 (7.0,11.0)

  

Time to complete radiotherapy c

  

t = 0.89

0.375

 n

40

18

  

 Mean ± SD

43.55 ± 6.91

45.22 ± 5.80

  

Whether bone pain occurs

  

χ2 = 1.99

0.159

 Yes

1 (2.50%)

3 (16.67%)

  

 No

39 (97.50%)

15 (83.33%)

  
  1. aCalculate the duration of 3/4 degree arrhythmia for subjects who have developed 3/4 degree arrhea
  2. bCalculate the delay time of chemotherapy for subjects who have delayed chemotherapy
  3. cCalculate the duration between the begining and the ending of radiotherapy in the concurrent chemoradiotherapy cycle of the subjects