Table 3 miRNA-mRNA target pairs with potential functional significance identified in HPV16 E6/E7 expressing HFKs

 hsa-miR-106a-5p

ARL9, BMP8B, CABLES1, CCL5, DUSP2, EGLN3, FZD9, MANEAL, NPNT, NRIP3, QRFPR, RAB42, RTN2, TIMP2, TNFAIP8L1, WNK3, ZNF454, ZYG11A

ACER2, CDKN1A, DCBLD2, FBXL7, HIST1H2BD, HIST1H2BG, HS3ST1, MDM2, NABP1, PLS1, TP53INP1, ZMAT3, ZNF665

 hsa-miR-10a-5p

ABCG2, C5, CHDH, FZD2, LRFN1, MRC2, RAB15, SAPCD2, SPARC, TCF15

ARHGAP18, CADM1, POU2F2, TFPI

 hsa-miR-132-3p

CCDC169, FKBP10, HS3ST3B1, LFNG, LOXL1, OLFML2A, SYT14

ADAMTSL1, ANKRD29, BDNF, CDKN1A, FAT3, LIFR, PTGS2, RNF128, TFPI

 hsa-miR-139-5p

ADAMTS17

NOTCH1, PEX5L

 hsa-miR-143-3p

ANKRD9, COL1A1, COL3A1, COL5A1, CREG2, IGFBP5, IKZF3, LRAT, SYT7

MDM2, PAPPA, PTGS2, TFPI

 hsa-miR-181b-5p

LMCD1, SCN8A, SLC35G2, TIMP3, ZNF415

HEPHL1, HIST1H3D, IL1A, ZNF439, ZNF788

 hsa-miR-181c-5p

KIT, SCN8A, SLC35G2, ZNF415

HEPHL1, HIST1H3D, IL1A, ZNF439, ZNF788

 hsa-miR-193a-3p

IGFBP5, RGMA

C12orf5, SLC10A6, ZMAT3

 hsa-miR-195-5p

AKT3, ALDH3B1, CYP26B1, FGFR4, FZD9, GPR27, INSR, RAB15, RASEF, RET,, WNK3, ZBTB16, ZNF704

BTN3A3, CDKN1A, HIST2H2BE, KRT33B, NEGR1, TM7SF3, ZFHX4, ZMAT3

 hsa-miR-196b-5p

PRUNE2

ACER2, HIST1H2BD, SLC9A7

 hsa-miR-20b-5p

BMP8B, CABLES1, CCL5, DUSP2, E2F2, EGLN3, FAM46C, FZD9, MANEAL, NPNT, NRIP3, QRFPR, RAB42, RTN2, TNFAIP8L1, WNK3, ZNF454, ZYG11A

ABCA1, ACER2, BTN3A3, CDKN1A, FBXL7, HIST1H2BD, HIST1H2BG, HS3ST1, MDM2, NABP1, PLS1, SAMD9L, TP53INP1, ZMAT3, ZNF665

 hsa-miR-224-5p

F8A2, F8A3, KLK1, RAB15

ENC1, SLC46A3

 hsa-miR-27b-5p

CD248

C15orf52, CXCL1, HIST1H2BD

 hsa-miR-335-5p

ACOT4, AKAP12, APOC1, AQP10, ARSI, ASCL2, BZRAP1, C12orf56, C7orf31, CACNA2D4, CACNG4, CDKN1C, CELSR3, CHRNB4, CLEC11A, CLMN, CNIH2, CNTD2, COL3A1, COL8A2, COL9A2, CPAMD8, CRIP2, CTHRC1, CTSF, CTXN1, DAPK2, DDN, DNALI1, DNMT3B, FAM46C, FBLN2, FBLN5, FZD1, FZD10, GATS, GCK, GIPC2, GJB6, GPR156, GPRIN2, GRB7, HMHA1, HPDL, ICAM1, KCNK5, KIAA1644, KIF17, KIT, KLHL35, LFNG, LGR6, LHX6, LMCD1, LOXL1, LRAT, LSP1, MARCKSL1, MATK, MEIS3, MOV10L1, NDUFA4L2, NECAB1, NEFH, NEFM, NINL, NR4A1, NRK, OLFML2A, PCED1A, PCSK4, PDE2A, PIWIL4, PLEKHG4, PLLP, PLXND1, PODXL2, PPP1R36, PYGM, RAD9B, RASA4B, RASIP1, RBP1, RGCC, RSPO4, RTN2, SELENBP1, SLCO4A1, STOX1, SUSD3, SYNGR3, SYNPO2, SYT12, SYT14, TBXAS1, TCEA3, TERT, TIMP3, TMCC2, TNC, TNS1, TPPP3, TRIM73, TRIM74, TRPV4, TSLP, VASN, WNT10B, WNT3, WNT7B, WNT9A, YBX2, ZFYVE28, ZG16B, ZNF157

ABCA12, ADAM21, ADH6, ANKRD29, ANO1, ATP9A, BARX2, BCHE, BHLHE41, BIK, BTN3A3, C20orf197, CDKN1A, CEP85L, CHI3L2, CLCA4, CNTNAP3B, CORO2B, CUL9, CXCL2, CXCL3, CXCR2, CYP3A5, CYP4F22, CSF1, CST6, DAB2, EHF, FAAH2, FABP6, FAM198B, FAM26E, FAM49A, FCRLA, FLG2, FOXA2, GCH1, GCNT2, GCNT4, GDF15, GREB1, GRIP2, HES2, HMCN1, IL1A, IL33, IL36RN, IL6, ILDR1, IVL, KALRN, KLRK1, KRT4, LIF, LIFR, LPPR5, LRRK2, MDM2, MRGPRX3, NEURL2, NFKBIZ, NLRP10, PAK3, PCDHGC5, PIFO, PLEKHG1, PLIN4, PTGS2, RASGRP1, SEC16B, SERPINB10, SLC2A13, SLC44A5, SLC46A3, SLC5A1, SLC9A7, SLPI, SPATA18, SPRR3, ST6GALNAC1, TCEAL7, TFPI, TP53INP1, TRIM22, ZEB1, ZPLD1

 hsa-miR-342-3p

HUNK, IGFBP5, IKZF3, EURL1B, QRFPR

HDAC9

 hsa-miR-3605-5p

ALDH3B1

LHX4, ZNF117

 hsa-miR-362-5p

HHIPL1, KCNK5

CT62

 hsa-miR-363-3p

SOX11

CDKN1A, GM2A, MDM2, S1PR1, TLR3

 hsa-miR-375

DNMT3B, DOK7, DPYSL3, FZD4, LIMD2, NCAM1, RTN2, TNNI3, TNS1, VASN

LYPD5, SEMA3C, SESN1, VPS37D

 hsa-miR-497-5p

AKT3, ALDH3B1, CYP26B1, FGFR4, FZD9, GPR27, RAB15, RASEF, WNK3, ZBTB16, ZNF704

BTN3A3, HIST2H2BE, KRT33B, NEGR1, TM7SF3, ZFHX4, ZMAT3

 hsa-miR-542-3p

FBLN5

MDM2, TFPI

 hsa-miR-615-5p

IGF2

–

 hsa-miR-99a-3p

–

SLC46A3

 hsa-miR-100-3p

SEMA5A

CXCL3, PVRL3

 hsa-miR-100-5p

IGF2

HIST2H2AA3, NLRP3

 hsa-miR-125b-5p

BMPR1B, CDKN2A, CYP24A1, E2F2, FZD4, GPRIN1, IGF2, IKZF3, NES, PLXND1, PTGS1, TBXAS1

GABRB3, HIST2H2BF, ID2, IKZF2, IL6, LIF, NEGR1, PRDM1, RASGRP1, S100A8, TNFAIP3, TP53INP1

 hsa-miR-1271-5p

GPC3, GPR156, PODXL, SERPINH1, SYNM

ACER2

 hsa-miR-127-3p

RGMA

PRDM1

 hsa-miR-127-5p

ATP2A3

MDM2, RHCG

 hsa-miR-136-3p

SOX11

–

 hsa-miR-138-5p

TERT

ARHGAP42, LCN2

 hsa-miR-221-5p

ENPP1, FZD2

–

 hsa-miR-34a-3p

–

TSPAN1

 hsa-miR-34a-5p

CDC25C, CDKN2A, GAS1, GPR156, KIT, PODXL, SLC35G2, VASN

C12orf5, HIST1H2AC, HIST1H3D, HIST1H4H, HIST2H2AA3, HIST2H2AA4, HIST2H2AC, HIST2H2BE, HIST4H4, NOTCH1, SAA1, VPS37D

 hsa-miR-34c-3p

SYNM

–

 hsa-miR-370-3p

SFMBT2

HES2, PEAR1

 hsa-miR-377-5p

CHDH

C12orf5, C3, FAM198B, GM2A, HIST1H2BD, TFPI, ZNF117

 hsa-miR-432-5p

ADAMTS17, NES, SPARC

MDM2, TFPI

 hsa-miR-485-3p

GAS1, HS3ST3B1

–

 hsa-miR-501-3p

EMP2

PLCB1

 hsa-miR-539-3p

GAS1, HS3ST3B1, PTPRS

–

 hsa-miR-543

ADAMTS17, COL5A1, PLXND1, TMPRSS4

SIPA1L2