A glycolysis-based three-gene signature predicts survival in patients with lung squamous cell carcinoma

BMC Cancer

Table 4 Univariate and multivariate Cox regression analysis of clinicopathologic factors and glycolysis-related genes signature for OS

Clinical features	Univariate analysis			Multivariate analysis
Clinical features	HR	95%CI of HR	P value	HR	95%CI of HR	P value
Age (> 65 vs. <=65)	1.376	1.000–1.892	0.050	1.489	1.078–2.055	0.016
Sex (Male vs. Female)	1.360	0.944–1.958	0.099	1.300	0.901–1.877	0.161
AJCC stage (III-IV vs. I-II)	1.392	0.974–1.989	0.070	1.185	0.716–1.962	0.510
T (T3 + T4 vs. T1 + T2)	1.412	0.973–2.048	0.069	1.335	0.845–2.110	0.216
M (M1 vs. M0)	2.432	0.898–6.591	0.080	2.216	0.768–6.399	0.141
N (N1 + N2 + N3 vs. N0)	1.062	0.780–1.444	0.704	1.087	0.765–1.545	0.642
Risk score (high risk vs. low-risk)	2.553	1.710–3.811	< 0.0001	2.663	1.790–3.962	< 0.0001

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