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Table 4 Univariate and multivariate Cox regression analysis of clinicopathologic factors and glycolysis-related genes signature for OS

From: A glycolysis-based three-gene signature predicts survival in patients with lung squamous cell carcinoma

Clinical features Univariate analysis Multivariate analysis
HR 95%CI of HR P value HR 95%CI of HR P value
Age (> 65 vs. <=65) 1.376 1.000–1.892 0.050 1.489 1.078–2.055 0.016
Sex (Male vs. Female) 1.360 0.944–1.958 0.099 1.300 0.901–1.877 0.161
AJCC stage (III-IV vs. I-II) 1.392 0.974–1.989 0.070 1.185 0.716–1.962 0.510
T (T3 + T4 vs. T1 + T2) 1.412 0.973–2.048 0.069 1.335 0.845–2.110 0.216
M (M1 vs. M0) 2.432 0.898–6.591 0.080 2.216 0.768–6.399 0.141
N (N1 + N2 + N3 vs. N0) 1.062 0.780–1.444 0.704 1.087 0.765–1.545 0.642
Risk score (high risk vs. low-risk) 2.553 1.710–3.811 < 0.0001 2.663 1.790–3.962 < 0.0001
  1. Abbreviations: OS Overall survival, HR Hazard ratio