Fig. 6
From: Predicting breast cancer drug response using a multiple-layer cell line drug response network model
Correlation between the predicted and observed drug responses using ML-CDN2 in CCLE. Many cell lines have an observed IC50 of 0.55 corresponding to the maximum dose of 8 μM in the CCLE IC50 curves. The true value of the IC50 for these points is 8 μM or higher. However, the IC50 values predicted by ML-CDN2 were not subject to this limitation. Therefore, we cannot see a good correlation between the predicted and observed IC50 values for the pairs that had an observed IC50 value of 8 μM or more