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Table 2 Surgery and neoadjuvant chemotherapy

From: Response to neoadjuvant chemotherapy based on pathologic complete response in very young patients with ER-positive breast cancer: a large, multicenter, observational study

Characteristic

ER-Positive

ER-Negative

Age<35

35≤Age<50

P-value

Age<35

35≤Age<50

P-value

(N = 147)

(N = 901)

(N = 134)

(N = 663)

Breast surgery

  

0.626

  

0.125

 Conserving

66 (44.9)

424 (47.1)

 

74 (55.2)

318 (48.0)

 

 Mastectomy

81 (55.1)

477 (52.9)

 

60 (44.8)

345 (52.0)

 

Axillary surgery

  

0.561

  

0.005

 SLNB

19 (16.4)

90 (10.0)

 

27 (20.1)

69 (10.4)

 

 SLNB➔ALND

43 (26.0)

269 (29.9)

 

27 (20.1)

174 (26.2)

 

 ALND

85 (56.2)

540 (59.9)

 

80 (59.7)

420 (63.3)

 

 Unknown

0 (0.0)

2 (0.3)

 

0 (0.0)

0 (0.0)

 

Neoadjuvant chemotherapy

  

0.090

  

0.068

 Anthracycline-based

111 (75.5)

689 (76.5)

 

107 (79.9)

504 (74.7)

 

 Trastuzumab-containg

13 (8.8)

515 (5.7)

0.138

5 (3.7)

58 (8.7)

0.053

 Others

8 (5.4)

94 (10.4)

 

9 (6.7)

82 (12.1)

 

 Unknown

28 (19.0)

118 (13.1)

 

18 (13.4)

89 (13.2)

 
  1. NOTE: Data are presented as No. (%) unless otherwise specified
  2. ER estrogen receptor, SLNB sentinel lymph node biopsy, ALND axillary lymph node dissection