Table 5 Multivariate analysis of predictors of overall survival for the subgroup of patients under and over 50 years of age
Age < 50 (N = 171) | Age ≥ 50 (N = 261) | |||||
|---|---|---|---|---|---|---|
HR | (95% CI) | P-value* | HR | (95% CI) | P-value* | |
Variable | ||||||
Female sex | 1.17 | (0.63, 2.16) | 0.62 | 0.51 | (0.30, 0.87) | 0.013 |
Age at diagnosis, per 10-year increase | 0.96 | (0.66, 1.39) | 0.83 | 1.11 | (0.83, 1.49) | 0.48 |
Marital status | 0.59 | 0.49 | ||||
Married/significant other | (ref) | (ref) | ||||
Single/separated/divorced | 1.20 | (0.63, 2.28) | 0.82 | (0.46, 1.45) | ||
Employment status | 0.56 | > 0.99 | ||||
Full time/part time/student | (ref) | (ref) | ||||
Unemployed/retired | 1.36 | (0.70, 2.62) | 1.00 | (0.55, 1.81) | ||
Unknown | 1.50 | (0.60, 3.73) | 1.00 | (0.43, 2.37) | ||
ADI WA decile, per 1-decile increase | 0.97 | (0.86, 1.09) | 0.58 | 0.93 | (0.84, 1.02) | 0.12 |
Tumor Characteristics | ||||||
Grade | 0.016 | 0.004 | ||||
1 | (ref) | (ref) | ||||
2 | 1.99 | (0.43, 9.27) | 1.44 | (0.57, 3.66) | ||
3 | 5.52 | (1.24, 24.50) | 2.87 | (1.20, 6.86) | ||
Unknown | 4.39 | (0.97, 19.97) | 0.86 | (0.30, 2.44) | ||
Maximum extent on imaging | 0.49 | 0.56 | ||||
≤ 5 cm | (ref) | (ref) | ||||
> 5 cm | 1.42 | (0.40, 5.00) | 1.43 | (0.64, 3.19) | ||
Unknown | 1.89 | (0.53, 6.68) | 1.13 | (0.50, 2.56) | ||
Treatment | ||||||
Time from diagnosis to first treatment, per 50% increase | 0.95 | (0.79, 1.15) | 0.61 | 1.00 | (0.85, 1.18) | 0.97 |