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Fig. 1 | BMC Cancer

Fig. 1

From: Genomic stratification based on microenvironment immune types and PD-L1 for tailoring therapeutic strategies in bladder cancer

Fig. 1

Immune subgroups according to PD-L1 expression and the type of immune modulation. a Immune modulation in the response of immune subgroups is indicated by the heatmap. Each row indicates a gene, and each column indicates a sample. b Kaplan-Meier plot showing that the active (red) and exhausted (blue) groups were not significantly different, P = 0.0984. c The exhausted group showed higher PD-L1 mRNA expression than the active group (1.54 vs 1.22, P = 0.012). d Representative immunohistochemical staining of PD-L1. Right: strong PD-L1 expression; left: negative PD-L1 expression. Original magnification: × 400. e Kaplan-Meier plot showing that PD-L1 overexpression predicts worse survival outcomes in bladder cancer. f Kaplan-Meier plot showing that different immune subgroups had significantly different prognoses

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BMC Cancer

ISSN: 1471-2407

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