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Table 6 Odds ratios and 95% confidence intervals showing the association of metabolic comorbidities and the risk of recurrent metastatic disease in pre- (N = 306) and post-menopausal breast cancer patients (N = 775) using binominal logistic regression. All variables were included in the multivariable analysis

From: Metabolic comorbidities and the association with risks of recurrent metastatic disease in breast cancer survivors

Variables

Pre-menopause (N = 306)

Post-menopause (N = 775)

OR

95%CI

P value

OR

95%CI

P value

DM or glucose intolerance

1.425

0.760–2.671

0.269

1.569

1.110–2.217

0.011

Dyslipidemia

0.816

0.426–1.565

0.541

1.142

0.805–1.621

0.456

Hypertension

0.686

0.395–1.191

0.181

1.151

0.828–1.600

0.401

BMI risk (> 27.7)

0.629

0.314–1.263

0.193

1.229

0.851–1.775

0.271

DM/glucose intolerance + Dyslipidemia

1.935

0.774–4.839

0.546

1.714

1.134–2.591

0.011

DM/glucose intolerance + Hypertension

1.257

0.610–2.592

0.535

1.705

1.191–2.441

0.004

Dyslipidemia + Hypertension

0.785

0.395–1.559

0.899

1.240

0.871–1.765

0.233

Dyslipidemia + BMI risk

0.602

0.164–2.211

0.445

1.133

0.715–1.793

0.595

Hypertension + BMI risk

0.335

0.097–1.161

0.084

1.317

0.881–1.970

0.180

DM/glucose intolerance + BMI risk

0.274

0.034–2.224

0.226

1.404

0.827–2.384

0.209

≥3 metabolic comorbidities

1.083

0.489–2.399

0.845

1.967

1.377–2.810

< 0.001

Any metabolic comorbidity

0.727

0.444–1.191

0.206

1.088

0.775–1.526

0.626