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Table 4 Odds ratios and 95% confidence intervals for association individual and concurrent metabolic comorbidities and risk of locoregional progression using binominal logistic regression, N = 1081. Individual and concurrent metabolic variables were included in the multivariable analysis

From: Metabolic comorbidities and the association with risks of recurrent metastatic disease in breast cancer survivors

Presence of metabolic comorbidities

With locoregional progression

N (%)

Without locoregional progression N (%)

OR

95%CI

P value

DM or glucose intolerance

149 (25.2%)

138 (28.2%)

0.853

0.650–1.118

0.249

Dyslipidemia

153 (25.8%)

146 (29.7%)

0.786

0.524–1.132

0.172

Hypertension

237 (41.9%)

225 (45.9%)

0.850

0.671–1.161

0.213

BMI risk

132 (22.3%)

120 (24.6%)

0.886

0.682–1.201

0.386

DM/glucose intolerance + Dyslipidemia

76 (12.8%)

71 (14.4%)

0.886

0.625–1.256

0.496

DM/glucose intolerance + Hypertension

123 (20.8%)

112 (22.8%)

0.860

0.643–1.151

0.311

Dyslipidemia + Hypertension

145 (24.5%)

134 (27.3%)

0.789

0.614–1.142

0.296

Dyslipidemia + BMI risk

62 (10.5%)

63 (12.8%)

0.771

0.621–1.201

0.252

Hypertension + BMI risk

86 (14.5%)

85 (17.3%)

0.803

0.661–1.193

0.241

DM/glucose intolerance + BMI risk

40 (6.8%)

42 (8.5%)

0.775

0.494–1.216

0.267

≥3 metabolic comorbidities

118 (20.0%)

110 (22.4%)

0.821

0.698–1.194

0.331

Any metabolic comorbidity

317 (53.6%)

289 (58.9%)

0.701

0.552–1.098

0.085