Variables | Survival time | Survival number and rate | Univariate analysis | |||||||
---|---|---|---|---|---|---|---|---|---|---|
Number | Mean survival time [95% CI] (months) | 1-year survival | 3-years survival | 5-years survival | ||||||
Total number | 140 | Â | Number | Rate [95%CI] | Number | Rate [95%CI] | Number | Rate [95%CI] | HR [95%CI] | P-value |
Age (years): | Â | Â | Â | Â | Â | Â | Â | Â | Â | 0.002 |
 00–24: | 1 | 16.00 | – | – | – | – | – | – | Ref |  |
 25–49: | 28 | 50.75 (35.20–66.30) | 22 | 78.57 (60.46–89.79) | 15 | 53.57 (35.81–70.47) | 9 | 32.14 (17.93–50.66) | 1.04 (0.14–7.58) | 0.97 |
 50–74: | 68 | 30.33 (21.98–38.68) | 36 | 52.94 (41.24–64.33) | 22 | 32.35 (22.44–44.16) | 15 | 22.06 (13.85–33.26) | 0.38 (0.23–0.63) | 0.00 |
  > 75: | 43 | 18.05 (10.82–25.28) | 20 | 46.51 (32.51–61.08) | 5 | 11.63 (5.07–24.48) | 2 | 4.65 (1.28–15.46) | 0.64 (0.43–0.96) | 0.03 |
Race: | Â | Â | Â | Â | Â | Â | Â | Â | Â | 0.20 |
 black: | 24 | 25.96 (15.72–36.20) | 15 | 62.50 (42.71–78.84) | 6 | 25.00 (12.00–44.90) | 3 | 12.50 (4.34–31.00) | Ref |  |
 other: | 9 | 16.78 (0.92–32.63) | 4 | 44.44 (18.88–73.33) | 1 | 11.11 (1.99–43.50) | 1 | – | 1.25 (0.79–1.96) | 0.34 |
 white: | 107 | 33.05 (25.82–40.29) | 60 | 56.07 (46.62–65.11) | 35 | 32.71 (24.55–42.06) | 22 | 20.56 (13.99–29.17) | 1.73 (0.87–3.43) | 0.12 |
Sex: | Â | Â | Â | Â | Â | Â | Â | Â | Â | 0.24 |
 Female: | 85 | 33.29 (25.58–41.01) | 49 | 57.65 (47.04–67.60) | 27 | 31.76 (22.84–42.27) | 18 | 21.18 (13.84–31.01) | Ref |  |
 Male: | 55 | 26.84 (17.73–35.94) | 30 | 54.55 (41.52–66.97) | 15 | 27.27 (17.28–40.23) | 8 | 14.55 (7.56–26.16) | 0.82 (0.58–1.15) | 0.25 |
Marital status: | Â | Â | Â | Â | Â | Â | Â | Â | Â | 0.78 |
 Married: | 75 | 32.57 (23.89–41.25) | 45 | 60.00 (48.69–70.34) | 21 | 28.00 (19.10–39.04) | 14 | 18.67 (11.46–28.93) | Ref |  |
 Unmarried: | 26 | 31.54 (16.84–46.24) | 13 | 50.00 (32.06–67.94) | 10 | 38.46 (22.43–57.47) | 6 | 23.08 (11.03–42.05) | 0.87 (0.43–1.76) | 0.70 |
 Separated: | 30 | 25.96 (15.40–36.52) | 14 | 46.67 (30.23–63.86) | 9 | 30.00 (16.66–47.88) | 5 | 16.67 (7.34–33.56) | 0.86 (0.40–1.87) | 0.71 |
 Unknown: | 9 | 28.00 (15.45–40.55) | – |  | – |  | – |  | – | – |
Insurance: | Â | Â | Â | Â | Â | Â | Â | Â | Â | 0.002 |
 Yes: | 105 | 28.06 (22.56–33.56) | 63 | 60.00 (50.44–68.86) | 30 | 28.57 (20.81–37.85) | 18 | 17.14 (11.13–25.48) | Ref |  |
 No: | 8 | 10.25 (0.00–22.04) | 1 | 12.50 (2.24–47.09) | 1 | 12.50 (2.24–47.09) | 0 | – | 1.96 (1.18–3.27) | 0.009 |
 unknown | 27 | 48.54 (27.33–69.76) |  |  |  |  |  |  | – | – |
Tumor grade: | Â | Â | Â | Â | Â | Â | Â | Â | Â | 0.00 |
 I: | 56 | 47.57 (37.67–57.48) | 50 | 89.29 (78.53–95.00) | 28 | 50.00 (37.33–62.67) | 16 | 28.57 (18.42–41.48) | Ref |  |
 II: | 25 | 41.84 (27.99–55.68) | 18 | 72.00 (52.42–85.72) | 11 | 44.60 (26.67–62.93) | 8 | 32.00 (17.21–51.59) | 0.16 (0.08–0.32) | 0.00 |
 III: | 47 | 9.57 (4.66–14.48) | 11 | 23.40 (13.60–37.22) | 2 | 4.26 (1.17–14.25) | 1 | 2.13 (0.38–11.11) | 0.20 (0.10–0.41) | 0.29 |
 IV: | 12 | 5.58 (0.00–12.36) | 1 | 8.33 (1.49–35.39) | 0 | – | 0 | – | 0.71 (0.37–1.34) | 0.00 |
 Unknown: | 0 |  |  |  |  |  |  |  |  |  |
Tumor size: | Â | Â | Â | Â | Â | Â | Â | Â | Â | 0.44 |
  < 3 cm: | 22 | 35.14 (16.93–53.34) | 13 | 59.09 (38.73–76.74) | 7 | 31.82 (16.36–52.68) | 5 | 22.73 (10.12–43.44) | Ref |  |
 3-5 cm: | 18 | 32.39 (16.70–48.09) | 11 | 61.11 (38.62–79.69) | 6 | 33.33 (16.28–56.25) | 4 | 22.22 (9.00–45.21) | 0.61 (0.35–1.08) | 0.09 |
 5-10 cm: | 32 | 32.22 (19.53–44.91) | 18 | 56.25 (39.33–71.83) | 12 | 37.50 (22.93–54.75) | 7 | 21.88 (11.02–38.75) | 0.72 (0.41–1.29) | 0.28 |
  > 10 cm: | 34 | 33.98 (21.33–46.62) | 20 | 58.82 (42.22–73.63) | 11 | 32.35 (19.13–49.16) | 7 | 20.59 (10.35–36.80) | 0.73 (0.45–1.20) | 0.21 |
 Unknown: | 34 | 21.88 (13.10–30.65) |  |  |  |  |  |  | – | – |
Lymph node invasion: | Â | Â | Â | Â | Â | Â | Â | Â | Â | 0.007 |
 No: | 115 | 32.72 (26.30–39.30) | 71 | 61.74 (52.61–70.11) | 38 | 33.04 (25.12–42.07) | 23 | 20.00 (13.71–28.23) | Ref |  |
 Yes: | 12 | 13.00 (0.54–25.46) | 5 | 41.67 (19.33–68.05) | 3 | 25.00 (8.89–53.23) | 1 | 8.33 (1.49–35.39) | 0.89 (0.49–1.63) | 0.09 |
 Unknown: | 13 | 29.58 (3.69–55.48) |  |  |  |  |  |  | – | – |
Total tumor number: | Â | Â | Â | Â | Â | Â | Â | Â | Â | 0.27 |
 1: | 92 | 33.46 (25.89–41.04) | 54 | 58.70 (48.48–68.21) | 30 | 32.61 (23.89–42.72) | 20 | 21.74 (14.54–31.21) | Ref |  |
 2: | 36 | 22.19 (14.10–30.29) | 20 | 55.56 (39.58–70.46) | 9 | 25.00 (13.75–41.07) | 3 | 8.33 (2.87–21.83) | 2.08 (0.29–14.99) | 0.47 |
 3: | 11 | 32.18 (2.96–61.41) | 5 | 45.45 (21.27–71.99) | 2 | 18.18 (5.14–47.70) | 1 | 9.09 (1.62–37.74) | 2.94 (0.40–21.62) | 0.29 |
 4: | 1 | 78.00 | 1 | – | 1 | – | 1 | – | 2.13 (0.27–16.66) | 0.47 |
AFP: | Â | Â | Â | Â | Â | Â | Â | Â | Â | 0.12 |
 Elevated: | 12 | 21.67 (3.82–39.52) | 4 | 33.33 (13.81–60.94) | 3 | 25.00 (8.89–53.23) | 3 | 25.00 (8.89–53.23) | Ref |  |
 Normal: | 35 | 40.20 (25.43–54.97) | 20 | 57.14 (40.86–72.02) | 14 | 40.00 (25.55–56.43) | 10 | 28.57 (16.33–45.05) | 1.29 (0.70–2.37) | 0.41 |
 Unknown: | 93 | 28.24 (21.86–34.63) |  |  |  |  |  |  | – | – |
Fibrosis Score | Â | Â | Â | Â | Â | Â | Â | Â | Â | 0.78 |
 Fibrosis score 0–4: | 13 | 25.62 (10.57–40.66) | 7 | 53.85 (29.14–76.79) | 3 | 23.08 (8.18–50.26) | 2 | 15.38 (4.33–42.23) | Ref |  |
 Fibrosis score 5–6: | 2 | 39.00 (0.00–115.44) | 1 | – | 1 | – | 1 | – | 1.21 (0.68–2.15) | 0.51 |
 Unknown: | 125 | 31.12 (24.76–37.49) |  |  |  |  |  |  | – | – |
Surgery | Â | Â | Â | Â | Â | Â | Â | Â | Â | 0.00 |
 Yes: | 45 | 54.16 (42.34–65.98) | 40 | 88.89 (76.50–95.16) | 26 | 57.78 (43.30–71.03) | 19 | 42.22 (28.97–56.70) | Ref |  |
 No: | 95 | 19.25 (14.03–24.48) | 39 | 41.05 (31.70–51.10) | 16 | 16.84 (10.64–25.62) | 7 | 7.37 (3.61–14.44) | 0.38 (0.26–0.56) | 0.00 |
Chemotherapy: | Â | Â | Â | Â | Â | Â | Â | Â | Â | 0.34 |
 Yes: | 34 | 25.68 (15.71–35.64) | 18 | 52.94 (36.74–68.55) | 8 | 23.53 (12.44–40.00) | 4 | 11.76 (4.67–26.62) | Ref |  |
 No/unknown: | 106 | 32.43 (25.32–39.54) | 61 | 57.55 (48.04–66.53) | 34 | 32.08 (23.95–41.45) | 22 | 20.75 (14.12–29.43) | 1.21 (0.82–1.79) | 0.35 |
Radiation: | Â | Â | Â | Â | Â | Â | Â | Â | Â | 0.97 |
 Yes: | 4 | 29.75 (18.09–41.41) | 3 | 75.00 (30.06–95.44) | 2 | 50.00 (15.00–85.00) | 0 | – | Ref |  |
 No/unknown: | 136 | 30.75 (24.69–36.82) | 75 | 55.15 (46.76–63.25) | 40 | 29.41 (22.40–37.55) | 26 | 19.12 (13.39–26.54) | 1.02 (0.37–2.77) | 0.97 |