Table 2 Association of age at diagnosis with clinical characteristics
From: Treatment patterns and outcomes of older patients with mantle cell lymphoma in an Asian population
Characteristic | Age (years) | p-value | |
|---|---|---|---|
|  | ≥ 60 | < 60 |  |
Total | 32 (48.5%) | 34 (51.5%) | – |
Sex | |||
 Male (48) | 24 (75%) | 24 (70.6%) | 0.6898 |
 Female (18) | 8 (25%) | 10 (29.4%) |  |
Ethnicity | |||
 Chinese (50) | 23 (71.9%) | 27 (79.4%) | 0.4786 |
 Other (16) | 9 (28.1%) | 7 (20.6%) |  |
Smoking history | |||
 Yes (9) | 4 (12.5%) | 5 (14.7%) | 1.0000 |
 No (57) | 28 (87.5%) | 29 (85.3%) | |
B-symptoms | |||
 Absent (29) | 8 (25%) | 21 (61.8%) | 0.0028 |
 Present (37) | 24 (75%) | 13 (38.2%) | |
ECOG performance status | |||
 0 (40) | 16 (50%) | 24 (70.6%) | 0.0896 |
 1–4 (26) | 16 (50%) | 10 (29.4%) | |
Ann Arbor stage | |||
 1–2 (9) | 4 (12.5%) | 5 (14.7%) | 1.0000 |
 3–4 (57) | 28 (87.5%) | 29 (85.3%) | |
sMIPI risk | |||
 Low/intermediate (20) | 5 (15.6%) | 15 (44.1%) | 0.0161 |
 High (46) | 27 (84.4%) | 19 (55.9%) | |
Bulky disease > 10 cm | |||
 Yes (6) | 3 (9.38%) | 3 (8.82%) | 1.0000 |
 No (57) | 28 (87.5%) | 29 (85.3%) | |
Spleen involved | |||
 Yes (20) | 10 (31.3%) | 10 (29.4%) | 0.8720 |
 No (46) | 22 (68.8%) | 24 (70.6%) |  |
Number of nodal sites | |||
 0–3 (26) | 11 (34.4%) | 15 (44.1%) | 0.4217 |
  ≥ 4 (40) | 21 (65.6%) | 19 (55.9%) | |
Extra-nodal involvement | |||
 Yes (54) | 24 (75%) | 30 (88.2%) | 0.2095 |
 No (12) | 8 (25%) | 4 (11.8%) | |
Bone marrow involvement | |||
 Positive (41) | 17 (53.1%) | 24 (70.6%) | 0.1469 |
 Negative (25) | 15 (46.9%) | 10 (29.4%) | |
Ki-67 expression (%) | |||
  > 30 (22) | 12 (37.5%) | 10 (29.4%) | 0.5593 |
  ≤ 30 (24) | 11 (34.4%) | 13 (38.2%) | |
Serum LDH | |||
 Elevated (35) | 18 (56.3%) | 17 (50%) | 0.4262 |
 Not elevated (29) | 12 (37.5%) | 17 (50%) | |
Albumin (g/L) | |||
  < 35 (18) | 11 (34.4%) | 7 (20.6%) | 0.1835 |
  ≥ 35 (47) | 20 (62.5%) | 27 (79.4%) | |
Hemoglobin (g/dL) | |||
  ≤ 12.4 (36) | 24 (75%) | 12 (35.3%) | 0.0013 |
  > 12.4 (30) | 8 (25%) | 22 (64.7%) | |
WBC (109 cells/L) | |||
  > 10 (19) | 10 (31.3%) | 9 (26.5%) | 0.6706 |
  ≤ 10 (47) | 22 (68.8%) | 25 (73.5%) | |