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Table 1 Clinical and demographic characteristics of patients with MCL in our cohort

From: Treatment patterns and outcomes of older patients with mantle cell lymphoma in an Asian population

Characteristic

N (%)

Total

66 (100)

Age (years)

 Median (range)

59 (26 to 84)

  ≥ 60

32 (48.5)

  < 60

34 (51.5)

Sex

 Male

48 (72.7)

 Female

18 (27.3)

Ethnicity

 Chinese

50 (75.8)

 Malay

7 (10.6)

 Indian

3 (4.55)

 Others

6 (13.6)

Smoking history

 Yes

9 (13.6)

 No

57 (86.4)

B-symptoms

 Absent

45 (68.2)

 Present

21 (31.8)

ECOG performance status

 0

40 (60.6)

 1–4

26 (39.4)

Ann Arbor stage

 1–2

9 (18.2)

 3–4

57 (86.4)

sMIPI risk

 Low

20 (30.3)

 Intermediate

30 (45.5)

 High

16 (24.2)

Bulky disease > 10 cm

 Yes

6 (9.5)

 No

57 (90.5)

Spleen involved

 Yes

20 (30.3)

 No

46 (69.7)

Number of nodal sites

 0–3

26 (39.4)

  ≥ 4

40 (60.6)

Extra-nodal involvement

 Yes

54 (81.8)

 No

12 (18.2)

Bone marrow involvement

 Positive

41 (62.1)

 Negative

25 (37.9)

Ki-67 expression (%)

 

  > 30

22 (47.8)

  ≤ 30

24 (52.2)

Serum LDH

 

 Elevated

35 (54.7)

 Not elevated

29 (45.3)

Albumin (g/L)

 

  < 35

18 (27.7)

  ≥ 35

47 (72.3)

Hemoglobin (g/dL)

 

  ≤ 12.4

36 (54.5)

  > 12.4

30 (45.5)

WBC (109 cells/L)

 

  > 10

19 (28.8)

  ≤ 10

47 (71.2)

  1. Abbreviations: ECOG Eastern Cooperative Oncology Group, MIPI Mantle Cell International Prognostic Index, LDH lactate dehydrogenase, WBC white blood cell count
  2. Variables unknown include: presence of bulky disease > 10 cm (n = 3), Ki-67 expression (n = 20), serum albumin (n = 1), serum LDH (n = 2)