Table 1 Baseline characteristics, EORTC QLQ-C30 scores and EQ-5D-5L scores (ITT population)
Characteristic | D-VMP (n = 350) | VMP (n = 356) |
|---|---|---|
Age, years | ||
Mean (SD) | 71.3 (6.66) | 71.5 (5.82) |
< 65, n (%) | 36 (10.3) | 24 (6.7) |
65 to < 75, n (%) | 210 (60.0) | 225 (63.2) |
≥ 75, n (%) | 104 (29.7) | 107 (30.1) |
Male, n (%) | 160 (45.7) | 167 (46.9) |
Race, n (%) | ||
White | 297 (84.9) | 304 (85.4) |
Black or African American | 3 (0.9) | 3 (0.8) |
Asian | 47 (13.4) | 45 (12.6) |
Other, Unknown or Not reported | 3 (0.9) | 4 (1.1) |
ECOG performance status, n (%) | ||
0 | 78 (22.3) | 99 (27.8) |
1 | 182 (52.0) | 173 (48.6) |
2 | 90 (25.7) | 84 (23.6) |
EORTC QLQ-C30 GHS score, mean (SD) | ||
GHS | 50.74 (20.996) | 52.40 (22.691) |
EORTC QLQ-C30 functional scores, mean (SD) | ||
Physical functioning | 59.96 (26.756) | 63.65 (25.701) |
Role functioning | 57.54 (34.250) | 61.06 (33.192) |
Emotional functioning | 69.70 (24.735) | 71.10 (22.304) |
Cognitive functioning | 80.49 (21.998) | 83.38 (19.948) |
Social functioning | 70.41 (28.468) | 70.64 (28.651) |
EORTC QLQ-C30 symptom scores, mean (SD) | ||
Pain | 46.10 (33.130) | 43.12 (31.429) |
Fatigue | 42.48 (25.661) | 41.05 (25.798) |
Nausea/vomiting | 5.38 (12.425) | 5.45 (13.566) |
Dyspnea | 18.35 (24.930) | 19.37 (24.742) |
Insomnia | 29.54 (30.044) | 27.93 (31.135) |
Appetite loss | 22.26 (28.116) | 21.81 (26.623) |
Constipation | 23.00 (31.517) | 18.86 (27.404) |
Diarrhea | 5.91 (17.015) | 5.40 (15.270) |
Financial difficulties | 18.88 (26.534) | 17.33 (24.743) |
EQ-5D-5L scores, mean (SD) | (n = 316) | (n = 325) |
VAS | 57.72 (20.254) | 60.32 (20.556) |