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Table 4 Comparative analysis between PN followed by PN subgroups (synchronous vs. metachronous) [latter surgery]

From: Evaluation of functional outcome of bilateral kidney tumors after sequential surgery

Variables

Synchronous

(N = 29 patients)

Metachronous

(N = 19 patients)

P value

Preoperative eGFR, ml/min/1.73 m2, mean (SD)

76.5 ± 22.4

82.1 ± 25.1

0.434

aLatest eGFR, ml/min/1.73 m2, mean (SD)

80.2 ± 24.0

78.1 ± 31.2

0.247

eGFR decline from baseline, mean (SD)

 Postoperative 1 week

6.5 ± 18.0

7.4 ± 19.7

0.871

 Postoperative 1 month

3.0 ± 14.9

8.4 ± 15.1

0.230

 Postoperative 1 year

3.5 ± 17.5

9.3 ± 17.5

0.266

bLatest

−3.7 ± 24.1

4.0 ± 19.5

0.250

De novo CKD, stage ≥3

 Baseline CKD, Before 1st surgery

7 (24.1%)

1 (5.3%)

0.123

 Baseline CKD, Before 2nd surgery

5 (17.2%)

1 (5.3%)

0.381

 De novo, ≤ 1 year after 2nd surgery

5 (17.2%)

4 (21.1%)

1.000

 De novo, > 1 year after 2nd surgery

0 (0%)

0 (0%)

1.000

Total number of pts. with CKD at last follow-up

10 (34.5%)

5 (26.3%)

0.751

  1. aLatest eGFR: The very last estimated Glomerular Filtration Rate measured during the follow-up period
  2. bLatest: The last time a patient was followed-up and evaluated eGFR