Skip to main content

Table 3 Multivariable analysis of death in the landmark population

From: Chemotherapy-induced neutropenia and treatment efficacy in advanced non-small-cell lung cancer: a pooled analysis of 6 randomized trials

 

Landmark population

(358 events / 572 patients)

HRa

(95% CI)

P

Chemotherapy-induced neutropenia

  

0.048

 Grade 1–2 vs 0

1.21

(0.92–1.58)

 

 Grade 3–4 vs 0

0.71

(0.53–0.95)

 

Age (continuous)

1.03

(1.01–1.05)

0.002

Gender

  

0.066

 Female vs Male

0.77

(0.58–1.01)

 

Performance status

  

0.181

 2 vs 0–1

1.98

(0.73–5.39)

 

Stage

  

0.156

 IV vs IIIB

1.29

(0.91–1.82)

 

Histology

  

0.13

 Non squamous vs Squamous

0.91

(0.68–1.20)

 

 Undefined vs Squamous

1.27

(0.89–1.81)

 
  1. aStratified by treatment arm