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Table 2 Risk variables for regional lymph nodes metastasis determined by univariate and multivariate logistic regression analyses

From: Nomogram for predicting preoperative regional lymph nodes metastasis in patients with metaplastic breast cancer: a SEER population-based study

Characteristics Univariate analysis Multivariate analysis
OR P value 95% CI OR P value 95% CI
Age (years)
 ≤ 60 Reference    Reference   
 > 60 0.82 0.096 0.65–1.04 0.85 0.199 0.66–1.09
Race
 White Reference    Reference   
 Black 1.16 0.335 0.86–1.57 0.98 0.883 0.71–1.35
 Othersa 1.25 0.325 0.80–1.95 1.12 0.639 0.70–1.78
Marital status
 Unmarried Reference    Reference   
 Married 0.73 0.010 0.58–0.93 0.80 0.089 0.62–1.03
 Unknown 0.83 0.560 0.43–1.58 0.95 0.875 0.48–1.87
Grade
 I Reference    Reference   
 II 2.07 0.119 0.83–5.16 1.83 0.208 0.71–4.68
 III 3.65 0.003 1.56–8.54 2.69 0.026 1.12–6.46
 IV 4.36 0.003 1.63–11.63 3.05 0.031 1.10–8.45
Laterality
 Right Reference    Reference   
 Left 0.82 0.094 0.65–1.04 0.79 0.058 0.62–1.01
ER status
 Negative Reference    Reference   
 Positive 1.49 0.007 1.12–1.98 1.60 0.006 1.14–2.23
PR status
 Negative Reference    Reference   
 Positive 1.08 0.644 0.77–1.52 0.97 0.870 0.65–1.44
Tumor size
 ≤ 2 cm Reference    Reference   
 > 2 cm and ≤ 5 cm 2.39 < 0.001 1.68–3.39 2.19 < 0.001 1.54–3.13
 > 5 cm 6.10 < 0.001 4.18–8.91 5.51 < 0.001 3.74–8.11
  1. OR Odds ratios, CI Confidential interval, ER Estrogen receptor, PR progesterone receptor
  2. aIncludes: American Indian, native Alaskan and Asian, Pacific Islander