Table 1 Demographic characteristics and clinical features of the population in our cohort
Variables | Total (n = 662) | % | IVa (n = 87) | % | IVb (n = 575) | % |
|---|---|---|---|---|---|---|
Age at diagnosis (years) | 49.0 (0–91.0) | 1.0 (0–76.0) | 51.0 (4–91.0) | |||
Children | 99 | 15.0 | 70 | 80.5 | 29 | 5.0 |
Adults | 563 | 85.0 | 17 | 19.5 | 546 | 95.0 |
Sex (Female/Male) | ||||||
Female | 293 | 44.3 | 45 | 51.7 | 248 | 43.1 |
male | 369 | 55.7 | 42 | 48.3 | 327 | 56.9 |
Race (White, Black, Other) | ||||||
White | 538 | 81.3 | 71 | 81.6 | 467 | 81.2 |
Black | 53 | 8.0 | 9 | 10.3 | 44 | 7.7 |
others | 71 | 10.7 | 7 | 8.0 | 64 | 11.1 |
Origin | ||||||
Non-Spanish-Hispanic-Latino | 572 | 86.4 | 73 | 83.9 | 499 | 86.8 |
Spanish-Hispanic-Latino | 90 | 13.6 | 14 | 16.1 | 76 | 13.2 |
ICD-O-3 Histology/behavior, malignant | ||||||
IV(a) Neuroblastoma and ganglioneuroblastoma | 87 | 13.1 | ||||
9500/3:Neuroblastoma | 74 | 11.2 | 74 | 85.1 | ||
9490/3:Ganglioneuroblastoma (GNB) | 13 | 1.9 | 13 | 14.9 | ||
IV(b) Other peripheral nervous cell tumors | 575 | 86.9 | ||||
8680/3: Paraganglioma, malignant | 14 | 2.1 | 14 | 2.4 | ||
9522/3:Esthesioneuroblastoma (ENB) | 559 | 84.4 | 559 | 97.2 | ||
9501/3:Medulloepithelioma,malignant | 1 | 0.2 | 1 | 0.2 | ||
9503/3: Neuroepithelioma, malignant | 1 | 0.2 | 1 | 0.2 | ||
Primary Site labeled | ||||||
C30.0-Nasal cavity | 451 | 68.1 | 6 | 6.9 | 445 | 77.5 |
C31.0–31.9-Paranasal sinus | 119 | 18.0 | 8 | 9.2 | 111 | 19.3 |
C47.0-Periph nerves & autonomic nervous sys: head, face, neck | 45 | 6.8 | 39 | 44.8 | 6 | 1.0 |
C49.0-Conn, subcutaneous, other soft tis: head, face, neck | 36 | 5.4 | 30 | 34.5 | 6 | 1.0 |
others | 11 | 1.7 | 4 | 4.6 | 7 | 1.2 |
Diagnosis years | ||||||
< 1998 | 71 | 10.7 | 16 | 18.4 | 55 | 9.6 |
1998–2004 | 147 | 22.2 | 20 | 23.0 | 127 | 22.1 |
> 2004 | 444 | 67.1 | 51 | 58.6 | 393 | 68.3 |
SEER historic stage | ||||||
Localized | 198 | 29.9 | 31 | 35.6 | 167 | 29.0 |
regional | 294 | 44.4 | 47 | 54.0 | 247 | 43.0 |
distant | 170 | 25.7 | 9 | 10.3 | 161 | 28.0 |
Clinical Nodal status (cN0/cN+) | ||||||
cN0 | 420 | 63.4 | 43 | 49.4 | 377 | 65.6 |
cN+ | 240 | 36.6 | 44 | 50.6 | 198 | 34.4 |
Radiation therapy (No/Yes) | ||||||
No | 239 | 36.1 | 71 | 81.6 | 168 | 29.2 |
Yes | 423 | 63.9 | 16 | 18.4 | 407 | 70.8 |
Chemotherapy (No/Yes) | ||||||
No | 482 | 72.8 | 58 | 66.7 | 424 | 73.7 |
Yes | 180 | 27.2 | 29 | 33.3 | 151 | 26.3 |
Lymph node dissection (No/Yes) | ||||||
No | 566 | 85.5 | 38 | 43.7 | 528 | 91.8 |
Yes | 96 | 14.5 | 49 | 56.3 | 47 | 8.2 |
Follow-up time (months) | 76.0 (6.0–336.0) | 95.0 (6.0–317.0) | 74.0 (6.0–336.0) | |||