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Table 1 Comparison of baseline characteristics between the high- and low-CXI groups

From: Clinical significance of the cachexia index in patients with small cell lung cancer

Characteristic

LD

ED

High-CXI group (n = 83)

Low-CXI group (n = 24)

p

High-CXI group (n = 123)

Low-CXI group (n = 37)

p

Age

  

0.067

  

0.214

  < 70 years

52 (62.7%)

10 (41.7%)

 

69 (56.1%)

25 (67.6%)

 

  ≥ 70 years

31 (37.4%)

14 (58.3%)

 

54 (43.9%)

12 (32.4%)

 

 Median (IQR), years

66 (61–71)

70.5 (66–76.5)

0.033

68 (61–74)

68 (64–71)

0.754

ECOG PS

  

0.008

  

0.013

 0–1

74 (89.2%)

16 (66.7%)

 

98 (79.7%)

22 (59.5%)

 

 2–3

9 (10.8%)

8 (33.3%)

 

25 (20.3%)

15 (40.5%)

 

Smoking status

  

0.400

  

>  0.998

 Never-smoker

1 (1.2%)

1 (4.2%)

 

2 (1.6%)

0 (0.0%)

 

 Current/former smoker

82 (98.8%)

23 (95.8%)

 

121 (98.4%)

37 (100.0%)

 

Regimen

  

0.224

  

0.242

 Etoposide and platinum

83 (100.0%)

23 (95.8%)

 

114 (92.7%)

32 (86.5%)

 

 Irinotecan and cisplatin

0 (0.0%)

1 (4.2%)

 

9 (7.3%)

5 (13.5%)

 

Prophylactic cranial irradiation

  

0.132

  

0.006

 Yes

49 (59.0%)

10 (41.7%)

 

50 (40.7%)

6 (16.2%)

 

 No

34 (41.0%)

14 (58.3%)

 

73 (59.4%)

31 (83.8%)

 

Lactate dehydrogenase status (n = 72 in LD, n = 133 in ED)

  

0.339

  

0.474

 Normal

31 (57.4%)

8 (44.4%)

 

34 (34.0%)

9 (27.3%)

 

 Elevated

23 (42.6%)

10 (55.6%)

 

66 (66.0%)

24 (72.7%)

 

Median BMI (IQR), kg/m2

23.0 (20.8–25.2)

21.9 (20.1–23.8)

0.104

22.6 (20.7–24.5)

21.0 (19.9–22.5)

0.007

  1. LD limited-stage disease, ED extensive-stage disease, CXI cachexia index, IQR interquartile range, ECOG PS Eastern Cooperative Oncology Group performance status, BMI body mass index