Table 5 Endometrial cancer, in patients with metastases in lymph nodes. Uni- and multivariable Cox proportional hazard regression analyzing overall survival including type of surgery, morphology, ploidy, lymphovascular space invasion and age
Variables | No. of patients | Univariable Cox regression | Multivariable Cox regression | ||
|---|---|---|---|---|---|
HR (95% CI) | p | HR (95% CI) | p | ||
Surgical approach | |||||
MIS | 64 | Ref. | Ref. | ||
Open surgery | 137 | 1.31 (0.70–2.45) | 0.40 | 1.36 (0.72–2.57) | 0.34 |
Endometrioid | |||||
Yes | 132 | Ref. | Ref. | ||
No | 69 | 2.81 (1.63–4.85) | < 0.001 | 1.87 (1.04–3.38) | 0.037 |
Ploidy | |||||
Diploid | 118 | Ref. | Ref | ||
Non-diploid | 83 | 2.65 (1.36–5.14) | 0.004 | 2.19 (1.09–4.40) | 0.029 |
LVSI | |||||
No | 61 | Ref. | Ref. | ||
Yes | 140 | 3.11 (1.41–6.90) | 0.005 | 3.10 (1.38–6.97) | 0.006 |
Age group (years) | |||||
0–59 | 43 | Ref. | Ref. | ||
60–69 | 72 | 1.28 (0.53–3.11) | 0.59 | 1.33 (0.55–3.24) | 0.53 |
70–79 | 68 | 2.84 (1.22–6.60) | 0.015 | 2.60 (1.11–6.12) | 0.028 |
80- | 18 | 3.08 (1.03–9.19) | 0.043 | 3.73 (1.22–11.4) | 0.021 |