Skip to main content

Table 1 The correlation between clinical parameters and RT use

From: Analysis of radiotherapy impact on survival in resected stage I/II pancreatic cancer patients: a population-based study

Clinical parameters

Stage I

Stage II

No RT

Neoadjuvant RT

adjuvant RT

P

No RT

Neoadjuvant RT

adjuvant RT

P

Age

   

0.626

   

<0.001

  < 60

471(29.2)

26(29.5)

123(31.7)

 

1822(22.4)

193(35.5)

1297(30.9)

 

  ≥ 60

1142(70.8)

62(70.5)

265(68.3)

 

6322(77.6)

351(64.5)

2903(69.1)

 

Year of diagnosis

   

<0.001

   

<0.001

 2004–2009

737(45.7)

34(38.6)

235(60.6)

 

3226(39.6)

158(29.0)

2101(50.0)

 

 2010–2015

876(54.3)

54(61.4)

153(39.4)

 

4918(60.4)

386(71.0)

2099(50.0)

 

Sex

   

0.002

   

0.133

 Female

916(56.8)

44(50.0)

183(47.2)

 

4038(49.6)

278(51.1)

2012(47.9)

 

 Male

697(43.2)

44(50.0)

205(52.8)

 

4106(50.4)

266(48.9)

2188(52.1)

 

Race

   

0.012

   

0.009

 Black

161(10.0)

12(13.6)

58(14.9)

 

751(9.2)

59(10.8)

394(9.4)

 

 White

1282(79.5)

72(81.8)

300(77.3)

 

6773(83.2)

466(85.7)

3492(83.1)

 

 Other

170(10.5)

4(4.5)

30(7.7)

 

620(7.6)

19(3.5)

314(7.5)

 

Primary tumor Site

   

<0.001

   

<0.001

 Head

880(54.6)

65(73.9)

251(64.7)

 

6285(77.2)

461(84.7)

3314(78.9)

 

 Body

233(14.4)

11(12.5)

56(14.4)

 

512(6.3)

36(6.6)

270(6.4)

 

 tail

381(23.6)

6(6.8)

54(13.9)

 

904(11.1)

22(4.0)

398(9.5)

 

 Pancreatic duct

26(1.6)

1(1.1)

7(1.8)

 

100(1.2)

1(0.2)

44(1.0)

 

 Overlapping

93(5.8)

5(5.7)

20(5.2)

 

343(4.2)

24(4.4)

174(4.1)

 

Pathological grade

   

<0.001

   

<0.001

 I

315(19.5)

12(13.6)

57(14.7)

 

768(9.4)

42(7.7)

370(8.8)

 

 II

608(37.7)

22(25.0)

202(52.1)

 

3781(46.4)

166(30.5)

2094(49.9)

 

 III

272(16.9)

18(20.5)

89(22.9)

 

2878(35.3)

106(19.5)

1450(34.5)

 

 IV

29(1.8)

0(0)

5(1.3)

 

112(1.4)

8(1.5)

53(1.3)

 

 Unknown

389(24.1)

36(40.9)

35(9.0)

 

605(7.4)

222(40.8)

233(5.5)

 

T

   

<0.001

   

0.002

 1

636(39.4)

20(22.7)

115(29.6)

 

157(1.9)

2(0.4)

75(1.8)

 

 2

977(60.6)

68(77.3)

273(70.4)

 

582(7.1)

23(4.2)

325(7.7)

 

 3

 

7405(90.9)

519(95.4)

3800(90.5)

 

N

   

   

<0.001

 0

 

2384(29.3)

256(47.1)

1025(24.4)

 

 1

 

5760(70.7)

288(52.9)

3175(75.6)

 

Chemotherapy

   

<0.001

   

<0.001

 No

1041(64.5)

3(3.4)

28(7.2)

 

3656(44.9)

8(1.5)

215(5.1)

 

 Yes

572(35.5)

85(96.6)

360(92.8)

 

4488(55.1)

536(98.5)

3985(94.9)

 

Surgical procedures

   

0.082

   

0.010

 Local excision of tumor

12(0.7)

1(1,1)

2(0.5)

 

27(0.3)

5(0.9)

19(0.5)

 

 Pancreatectomy

1411(87.5)

67(76.1)

341(87.9)

 

6916(84.9)

447(82.2)

3569(85.0)

 

 Extended

154(9.5)

15(17.0)

34(8.8)

 

1097(13.5)

78(14.3)

577(13.7)

 

 Unknown

36(2.2)

5(5.7)

11(2.8)

 

104(1.3)

14(2.6)

35(0.8)

 
  1. Abbreviations: RT Radiotherapy. Note: Pathological grade I, Well differentiated; II, Moderately differentiated; III, Poorly differentiated; IV, Undifferentiated; anaplastic. Pancreatectomy: partial pancreatectomy, local or partial pancreatectomy and duodenectomy with/without distal/partial gastrectomy, total pancreatectomy; Extended: total pancreatectomy and subtotal gastrectomy or duodenectomy, extended pancreatoduodenectomy