Fig. 7
From: KDM6B promotes ESCC cell proliferation and metastasis by facilitating C/EBPβ transcription
GSK-J4 inhibits proliferation, migration and invasion of ESCC cells. a KYSE150 cells were treated with the indicated concentrations of GSK-J4 for 24 h. western blots analysis the indicated antibodies. b The CCK-8 assay was used to determine cell proliferation of ESCC cells after treated with GSK-J4 for 24 h. c Representative images (left panel) and the statistical result (right panel) of cladogenesis abilities. d Representative images of cell cycle distribution (left panels) and statistical graphs of cell cycle changes (right panels). Cell scratch wound-healing assays e, Transwell migration and invasion experiment f detect the effect of GSK-J4 on migration and invasion ability KYSE150 cells. The bar graph shows the quantitative results of scratch healing and Transwell assay. Results are representative of three independent experiments and are expressed as the mean ± S.D. * p < 0.05, ** p < 0.01, *** p < 0.001