Fig. 3From: KDM6B promotes ESCC cell proliferation and metastasis by facilitating C/EBPβ transcriptionThe interference of KDM6B inhibits ESCC growth and distal pulmonary metastases in vivo. a Photographs of mice after subcutaneous xenografting injection with ESCC cells stably interfering KDM6B and Lv-control (n = 5). b Tumor growth curve of each group. c Tumor weight averages between control and sh-KDM6B-1 groups at the end of the experiment (Day 21). Data are presented as mean ± SD (n = 5). d Photographs of mice in lung tissues after tail veins injection with ESCC cells stably down expressed KDM6B and sh-NC. Hematoxylin and eosin staining of lung tissue isolated from nude mice that had been injected with ESCC cells stably down expressed KDM6B and sh-NC via lateral tail veins (magnification, × 200) (left panels). e The calculated number of metastases in mice that had received lateral tail injections. ** p < 0.01, *** p < 0.001Back to article page