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Table 1 Incident cases, deaths and DALYs of multiple myeloma in 2019, and percentage change of age-standardized rates by sex and GBD region

From: Measuring the global, regional, and national burden of multiple myeloma from 1990 to 2019

  Incidence Deaths DALYs
  Number of incident cases Age standardized incidence rate (per 100,000 population) Percentage change in rates(%), 1990–2019 Number of deaths Age standardized death rate (per 100,000 population) Percentage change in rates(%), 1990–2019 Number of DALYs*103 Age standardized DALY rate (per 100,000 population) Percentage change in rates(%), 1990–2019
Global 155,688 (136585–172,577) 1.92 (1.68–2.12) 10.99(−5.11–21.64) 113,474 (99527–121,735) 1.42 (1.24–1.52) 1.43(− 13.98–7.98) 2497.2 (2190.5–2722.7) 30.26 (26.58–32.9) −0.85(− 17.48–6.66)
Sex
 Females 71,171 (60343–80,140) 1.62 (1.38–1.83) 4.65(− 11.58–14.6) 53,029 (45149–58,252) 1.21 (1.03–1.33) −3.82(− 19.80–2.84) 1120.6 (967.7–1243.7) 25.67 (22.15–22.48) −6.11(− 23.87–1.17)
 Males 84,516 (70924–94,910) 2.28 (1.91–2.56) 16.03(− 1.45–29.18) 60,445 (50723–67,056) 1.68 (1.40–1.84) 5.7(− 9.92–14.3) 1376.6 (1150.6–1567.8) 35.51 (29.77–40.03) 3.4(− 14.14–13.72)
Socio-demographic index
 High SDI 72,250 (62610–82,520) 3.77 (3.29–4.33) 16.66 (5.06–32.25) 48,108 (41267–51,245) 2.4 (2.1–2.59) 2.29(− 3.93–11.12) 901.2 (811.9–1007.5) 49.3 (45.25–55.85) −2.41(− 8.13–13.1)
 High-middle SDI 37,329 (30933–41,806) 1.83 (1.52–2.05) 21.54(− 1.95–36.12) 27,224 (22937–29,555) 1.34 (1.13–1.45) 10.66(− 10.62–20.44) 605.9 (506.6–659.7) 29.77 (24.79–32.47) 5.33(− 15.84–15.34)
 Middle SDI 25,294 (20919–28,629) 1.01 (0.83–1.14) 19.55(− 14.5–36.97) 21,143 (17470–24,144) 0.86 (0.71–0.99) 11.68(− 21.22–27.39) 134.7 (107.4–158.1) 20.74 (16.96–23.57) 10.48(− 24.71–27.2)
 Low-middle SDI 13,654 (11831–15,809) 0.99 (0.86–1.15) 20.83(− 10–38.57) 12,040 (10183–14,016) 0.89 (0.76–1.05) 13.77(− 14.1–29.67) 312.7 (267.2–366.6) 21.75 (18.57–25.5) 14.19(− 14.94–31.05)
 Low SDI 5148 (4101–5981) 1 (0.8–1.16) 3.18(− 22.53–22.54) 4970 (3938–5768) 1.01 (0.8–1.17) 5.99(− 21.03–25.9) 540.9 (442.1–614.1) 24.16 (19.2–28.19) 5.2(− 22.32–27.82)
Region
 Andean Latin America 955 (747–1214) 1.71 (1.34–2.18) 16.08(− 25.14–55.8) 788 (622–995) 1.43 (1.13–1.8) 3.46(− 31.28–38.21) 18.9 (14.67–24.07) 33.29 (25.84–42.26) 1.6(− 34.2–38.53)
 Australasia 2658 (2101–3388) 5.33 (4.21–6.8) 25.1(− 0.82–60.03) 1541 (1328–1736) 2.97 (2.59–3.39) 6.38(− 4.64–24.37) 29.51 (26.16–34.07) 61.23 (54.51–70.45) 1.41(− 8.47–23.89)
 Caribbean 1686 (1401–1993) 3.25 (2.7–3.84) 27.38 (7.33–49.9) 1224 (1022–1442) 2.36 (1.97–2.79) 14.95(− 1.89–34.35) 28.86 (24.02–34.53) 55.51 (46.25–66.5) 16.62(− 0.97–38.02)
 Central Asia 608 (533–686) 0.8 (0.7–0.89) 33.1 (12.6–55.55) 502 (441–564) 0.69 (0.61–0.78) 30.58 (11.09–53.2) 14.33 (12.6–16.23) 17.57 (15.43–19.77) 32.24 (12.37–54.72)
 Central Europe 4550 (3599–5249) 2.13 (1.69–2.46) 37.47 (6.33–58.98) 3920 (3105–4499) 1.79 (1.42–2.06) 32.93 (3.41–52.72) 83.8 (67.12–96.4) 40.61 (32.49–46.85) 25.67 (2.27–44.11)
 Central Latin America 3927 (3269–4645) 1.65 (1.38–1.96) 44.69 (21.08–69.62) 3038 (2529–3589) 1.3 (1.08–1.53) 30.08 (7.57–52.46) 76.73 (62.57–91.25) 31.74 (25.98–37.71) 28.6 (6.83–50.76)
 Central Sub-Saharan Africa 630 (390–864) 1.2 (0.74–1.64) 3.84(− 23.17–36.26) 574 (355–783) 1.16 (0.71–1.56) 1.05(− 24.05–29.46) 15.98 (9.98–21.98) 27.62 (17.1–37.65) 0.37(− 26.39–32.62)
 East Asia 19,712 (14445–24,287) 0.94 (0.69–1.16) 32.75(− 28.14–71.32) 14,109 (10739–17,150) 0.68 (0.52–0.83) 6.05(− 39.47–35.18) 363.76 (271.11–439.32) 17.25 (12.7–20.81) 6.96(− 42.07–39.48)
 Eastern Europe 5358 (4643–6083) 1.57 (1.35–1.78) 42.09 (21.48–60.32) 3986 (3373–4508) 1.15 (0.97–1.31) 31.27 (10.61–49.17) 98.84 (82.51–112.1) 29.54 (24.6–33.43) 27.19 (10.77–44.01)
 Eastern Sub-Saharan Africa 2034 (1437–2501) 1.28 (0.91–1.56) 10.84(− 21.33–37.13) 1889 (1348–2308) 1.25 (0.89–1.52) 9.12(− 21.64–35.2) 50.82 (35.96–62.75) 28.94 (20.6–35.64) 6.58(− 25.49–36.05)
 High-income Asia Pacific 9191 (7132–10,888) 1.96 (1.58–2.3) 10.62(− 13.64–28.79) 6562 (5165–7282) 1.32 (1.07–1.45) −3.08(− 21.57–5.56) 113.04 (93.38–123.29) 26.62 (22.07–28.98) −8.67(− 27.89 - -0.88)
 High-income North America 30,394 (26016–36,835) 4.8 (4.12–5.87) 11.22(− 4.48–41.32) 19,942 (18012–22,920) 3.07 (2.8–3.58) −1.27(− 6.53–21.95) 388.96 (360.5–478.32) 63.18 (58.79–78.56) −7.85(− 12.97–21.41)
 North Africa and Middle East 6373 (4991–7641) 1.49 (1.17–1.77) 14.95(− 23.27–42.18) 5012 (3938–5969) 1.22 (0.96–1.44) 2.91(− 29.84–26.14) 130 (101.74–157.35) 28.4 (22.27–34.07) 0.13(− 33.47–23.52)
 Oceania 72 (48–115) 1.01 (0.69–1.55) − 0.74(− 18.92–23.18) 63 (42–100) 0.94 (0.64–1.43) −1.9(− 19.53–21.1) 1.83 (1.22–3.02) 22.99 (15.54–36.69) −2.57(− 21–22.71)
 South Asia 13,368 (9787–15,941) 0.95 (0.69–1.13) 16.5(− 18.11–42.11) 11,734 (8615–13,925) 0.86 (0.62–1.02) 8.87(− 24.09–31.24) 305.84 (228.24–362.7) 20.67 (15.34–24.47) 10.05(− 23.54–32.56)
 Southeast Asia 5003 (4174–6594) 0.82 (0.68–1.09) 14.96(− 11.79–37.09) 4194 (3495–5587) 0.71 (0.59–0.95) 7.02(− 17.05–25.43) 108.86 (90.98–142.69) 16.9 (14.12–22.27) 4.26(− 21.38–23.88)
 Southern Latin America 2212 (1728–2837) 2.66 (2.08–3.41) 28.04(− 2.34–64.15) 1739 (1584–2003) 2.07 (1.88–2.37) 14.63 (1.17–31.88) 38.12 (34.97–44.3) 46.4 (42.61–53.99) 12.67(− 1.76–32.19)
 Southern Sub-Saharan Africa 1267 (905–1467) 2.24 (1.6–2.59) 22.37(−3.98–45.5) 1108 (788–1283) 2.04 (1.45–2.35) 20.07(− 4.68–43.35) 29.17 (20.71–33.88) 48.73 (34.63–56.49) 17.56(− 9.33–38.88)
 Tropical Latin America 5004 (4350–5394) 2.06 (1.78–2.22) 46.2 (23.92–56.74) 4018 (3400–4313) 1.67 (1.41–1.8) 35.83 (12.05–45.67) 96.79 (85–105.43) 39.11 (34.15–42.37) 28.34 (11.91–36.39)
 Western Europe 38,981 (31727–44,710) 4.24 (3.51–4.9) 29.9 (10.88–48.41) 25,996 (21281–27,914) 2.64 (2.22–2.82) 15.62(−2.93–21.83) 461.63 (397.99–495.38) 52.87 (46.52–56.55) 7.97(− 5.58–15.07)
 Western Sub-Saharan Africa 1705 (1340–2074) 0.91 (0.72–1.11) 15.57(− 9.48–40.42) 1536 (1189–1882) 0.86 (0.67–1.05) 12.22(− 12.14–35.43) 41.44 (31.75–51.23) 20.47 (15.76–25.1) 11.51(− 13.72–37.56)