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Table 1 Incident cases, deaths and DALYs of multiple myeloma in 2019, and percentage change of age-standardized rates by sex and GBD region

From: Measuring the global, regional, and national burden of multiple myeloma from 1990 to 2019

 

Incidence

Deaths

DALYs

 

Number of incident cases

Age standardized incidence rate (per 100,000 population)

Percentage change in rates(%), 1990–2019

Number of deaths

Age standardized death rate (per 100,000 population)

Percentage change in rates(%), 1990–2019

Number of DALYs*103

Age standardized DALY rate (per 100,000 population)

Percentage change in rates(%), 1990–2019

Global

155,688 (136585–172,577)

1.92 (1.68–2.12)

10.99(−5.11–21.64)

113,474 (99527–121,735)

1.42 (1.24–1.52)

1.43(− 13.98–7.98)

2497.2 (2190.5–2722.7)

30.26 (26.58–32.9)

−0.85(− 17.48–6.66)

Sex

 Females

71,171 (60343–80,140)

1.62 (1.38–1.83)

4.65(− 11.58–14.6)

53,029 (45149–58,252)

1.21 (1.03–1.33)

−3.82(− 19.80–2.84)

1120.6 (967.7–1243.7)

25.67 (22.15–22.48)

−6.11(− 23.87–1.17)

 Males

84,516 (70924–94,910)

2.28 (1.91–2.56)

16.03(− 1.45–29.18)

60,445 (50723–67,056)

1.68 (1.40–1.84)

5.7(− 9.92–14.3)

1376.6 (1150.6–1567.8)

35.51 (29.77–40.03)

3.4(− 14.14–13.72)

Socio-demographic index

 High SDI

72,250 (62610–82,520)

3.77 (3.29–4.33)

16.66 (5.06–32.25)

48,108 (41267–51,245)

2.4 (2.1–2.59)

2.29(− 3.93–11.12)

901.2 (811.9–1007.5)

49.3 (45.25–55.85)

−2.41(− 8.13–13.1)

 High-middle SDI

37,329 (30933–41,806)

1.83 (1.52–2.05)

21.54(− 1.95–36.12)

27,224 (22937–29,555)

1.34 (1.13–1.45)

10.66(− 10.62–20.44)

605.9 (506.6–659.7)

29.77 (24.79–32.47)

5.33(− 15.84–15.34)

 Middle SDI

25,294 (20919–28,629)

1.01 (0.83–1.14)

19.55(− 14.5–36.97)

21,143 (17470–24,144)

0.86 (0.71–0.99)

11.68(− 21.22–27.39)

134.7 (107.4–158.1)

20.74 (16.96–23.57)

10.48(− 24.71–27.2)

 Low-middle SDI

13,654 (11831–15,809)

0.99 (0.86–1.15)

20.83(− 10–38.57)

12,040 (10183–14,016)

0.89 (0.76–1.05)

13.77(− 14.1–29.67)

312.7 (267.2–366.6)

21.75 (18.57–25.5)

14.19(− 14.94–31.05)

 Low SDI

5148 (4101–5981)

1 (0.8–1.16)

3.18(− 22.53–22.54)

4970 (3938–5768)

1.01 (0.8–1.17)

5.99(− 21.03–25.9)

540.9 (442.1–614.1)

24.16 (19.2–28.19)

5.2(− 22.32–27.82)

Region

 Andean Latin America

955 (747–1214)

1.71 (1.34–2.18)

16.08(− 25.14–55.8)

788 (622–995)

1.43 (1.13–1.8)

3.46(− 31.28–38.21)

18.9 (14.67–24.07)

33.29 (25.84–42.26)

1.6(− 34.2–38.53)

 Australasia

2658 (2101–3388)

5.33 (4.21–6.8)

25.1(− 0.82–60.03)

1541 (1328–1736)

2.97 (2.59–3.39)

6.38(− 4.64–24.37)

29.51 (26.16–34.07)

61.23 (54.51–70.45)

1.41(− 8.47–23.89)

 Caribbean

1686 (1401–1993)

3.25 (2.7–3.84)

27.38 (7.33–49.9)

1224 (1022–1442)

2.36 (1.97–2.79)

14.95(− 1.89–34.35)

28.86 (24.02–34.53)

55.51 (46.25–66.5)

16.62(− 0.97–38.02)

 Central Asia

608 (533–686)

0.8 (0.7–0.89)

33.1 (12.6–55.55)

502 (441–564)

0.69 (0.61–0.78)

30.58 (11.09–53.2)

14.33 (12.6–16.23)

17.57 (15.43–19.77)

32.24 (12.37–54.72)

 Central Europe

4550 (3599–5249)

2.13 (1.69–2.46)

37.47 (6.33–58.98)

3920 (3105–4499)

1.79 (1.42–2.06)

32.93 (3.41–52.72)

83.8 (67.12–96.4)

40.61 (32.49–46.85)

25.67 (2.27–44.11)

 Central Latin America

3927 (3269–4645)

1.65 (1.38–1.96)

44.69 (21.08–69.62)

3038 (2529–3589)

1.3 (1.08–1.53)

30.08 (7.57–52.46)

76.73 (62.57–91.25)

31.74 (25.98–37.71)

28.6 (6.83–50.76)

 Central Sub-Saharan Africa

630 (390–864)

1.2 (0.74–1.64)

3.84(− 23.17–36.26)

574 (355–783)

1.16 (0.71–1.56)

1.05(− 24.05–29.46)

15.98 (9.98–21.98)

27.62 (17.1–37.65)

0.37(− 26.39–32.62)

 East Asia

19,712 (14445–24,287)

0.94 (0.69–1.16)

32.75(− 28.14–71.32)

14,109 (10739–17,150)

0.68 (0.52–0.83)

6.05(− 39.47–35.18)

363.76 (271.11–439.32)

17.25 (12.7–20.81)

6.96(− 42.07–39.48)

 Eastern Europe

5358 (4643–6083)

1.57 (1.35–1.78)

42.09 (21.48–60.32)

3986 (3373–4508)

1.15 (0.97–1.31)

31.27 (10.61–49.17)

98.84 (82.51–112.1)

29.54 (24.6–33.43)

27.19 (10.77–44.01)

 Eastern Sub-Saharan Africa

2034 (1437–2501)

1.28 (0.91–1.56)

10.84(− 21.33–37.13)

1889 (1348–2308)

1.25 (0.89–1.52)

9.12(− 21.64–35.2)

50.82 (35.96–62.75)

28.94 (20.6–35.64)

6.58(− 25.49–36.05)

 High-income Asia Pacific

9191 (7132–10,888)

1.96 (1.58–2.3)

10.62(− 13.64–28.79)

6562 (5165–7282)

1.32 (1.07–1.45)

−3.08(− 21.57–5.56)

113.04 (93.38–123.29)

26.62 (22.07–28.98)

−8.67(− 27.89 - -0.88)

 High-income North America

30,394 (26016–36,835)

4.8 (4.12–5.87)

11.22(− 4.48–41.32)

19,942 (18012–22,920)

3.07 (2.8–3.58)

−1.27(− 6.53–21.95)

388.96 (360.5–478.32)

63.18 (58.79–78.56)

−7.85(− 12.97–21.41)

 North Africa and Middle East

6373 (4991–7641)

1.49 (1.17–1.77)

14.95(− 23.27–42.18)

5012 (3938–5969)

1.22 (0.96–1.44)

2.91(− 29.84–26.14)

130 (101.74–157.35)

28.4 (22.27–34.07)

0.13(− 33.47–23.52)

 Oceania

72 (48–115)

1.01 (0.69–1.55)

− 0.74(− 18.92–23.18)

63 (42–100)

0.94 (0.64–1.43)

−1.9(− 19.53–21.1)

1.83 (1.22–3.02)

22.99 (15.54–36.69)

−2.57(− 21–22.71)

 South Asia

13,368 (9787–15,941)

0.95 (0.69–1.13)

16.5(− 18.11–42.11)

11,734 (8615–13,925)

0.86 (0.62–1.02)

8.87(− 24.09–31.24)

305.84 (228.24–362.7)

20.67 (15.34–24.47)

10.05(− 23.54–32.56)

 Southeast Asia

5003 (4174–6594)

0.82 (0.68–1.09)

14.96(− 11.79–37.09)

4194 (3495–5587)

0.71 (0.59–0.95)

7.02(− 17.05–25.43)

108.86 (90.98–142.69)

16.9 (14.12–22.27)

4.26(− 21.38–23.88)

 Southern Latin America

2212 (1728–2837)

2.66 (2.08–3.41)

28.04(− 2.34–64.15)

1739 (1584–2003)

2.07 (1.88–2.37)

14.63 (1.17–31.88)

38.12 (34.97–44.3)

46.4 (42.61–53.99)

12.67(− 1.76–32.19)

 Southern Sub-Saharan Africa

1267 (905–1467)

2.24 (1.6–2.59)

22.37(−3.98–45.5)

1108 (788–1283)

2.04 (1.45–2.35)

20.07(− 4.68–43.35)

29.17 (20.71–33.88)

48.73 (34.63–56.49)

17.56(− 9.33–38.88)

 Tropical Latin America

5004 (4350–5394)

2.06 (1.78–2.22)

46.2 (23.92–56.74)

4018 (3400–4313)

1.67 (1.41–1.8)

35.83 (12.05–45.67)

96.79 (85–105.43)

39.11 (34.15–42.37)

28.34 (11.91–36.39)

 Western Europe

38,981 (31727–44,710)

4.24 (3.51–4.9)

29.9 (10.88–48.41)

25,996 (21281–27,914)

2.64 (2.22–2.82)

15.62(−2.93–21.83)

461.63 (397.99–495.38)

52.87 (46.52–56.55)

7.97(− 5.58–15.07)

 Western Sub-Saharan Africa

1705 (1340–2074)

0.91 (0.72–1.11)

15.57(− 9.48–40.42)

1536 (1189–1882)

0.86 (0.67–1.05)

12.22(− 12.14–35.43)

41.44 (31.75–51.23)

20.47 (15.76–25.1)

11.51(− 13.72–37.56)