Association of single nucleotide polymorphisms of cytochrome P450 enzymes with experience of vasomotor, vaginal and musculoskeletal symptoms among breast cancer patients: a systematic review

Table 2 The results of the critical appraisal of the included studies

Included study	Objectives described	Study design described	Study settings described	Eligibility criteria described	Variables defined	Sources of measures described	Statistical methods described	Characteristics of participants described	Main results reported	Interpretation of results provided	Score (Max. 10)
Argalacsova et al., 2017 [25]	No	No	Yes	Yes	No	No	Yes	Yes	No	Yes	5
Baxter et al., 2014 [26]	Yes	Yes	Yes	No	Yes	Yes	Yes	Yes	Yes	Yes	9
Dezentjé et al., 2014 [27]	Yes	No	No	Yes	Yes	Yes	Yes	Yes	Yes	Yes	8
Fox et al., 2016 [28]	Yes	No	No	Yes	Yes	Yes	Yes	Yes	No	Yes	7
Goetz et al., 2005 [29]	Yes	Yes	Yes	Yes	Yes	No	Yes	Yes	Yes	Yes	9
Henry et al., 2009 [30]	Yes	Yes	No	No	Yes	Yes	Yes	No	Yes	Yes	7
Jager et al., 2013 [31]	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	10
Jansen et al., 2018 [32]	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	10
Joffe et al., 2012 [33]	Yes	No	No	Yes	Yes	Yes	Yes	Yes	No	Yes	7
Johansson et al., 2016 [34]	Yes	Yes	No	No	Yes	Yes	Yes	Yes	Yes	Yes	8
Regan et al., 2012 [35]	Yes	Yes	No	No	Yes	Yes	Yes	Yes	Yes	Yes	8
Ruddy et al., 2013 [36]	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	No	Yes	9
Wickramage et al., 2017 [37]	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	10
Zembutsu et al., 2017 [38]	Yes	Yes	Yes	No	Yes	No	Yes	Yes	Yes	Yes	8

ISSN: 1471-2407