Table 2 Cancer frequencies by genotype
From: The contribution of Lynch syndrome to early onset malignancy in Ireland
Mutation | Affected | Malignancies | CRC | Endometrial | Breast | Small bowel | Ovarian | Urothelial | Other |
|---|---|---|---|---|---|---|---|---|---|
path_MLH1 | 48 | 62 | 36 | 7 | 2 | 2 | 3 | 0 | 12 |
path_MSH2 | 32 | 57 | 26 | 9 | 4 | 0 | 1 | 3 | 14 |
path_MSH6 | 8 | 10 | 4 | 3 | 2 | 0 | 0 | 1 | 0 |
path_PMS2 | 8 | 10 | 5 | 1 | 0 | 0 | 1 | 0 | 3 |
path_EPCAM | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Total | 97 | 140 | 71 | 20 | 9 | 2 | 5 | 4 | 29 |