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Table 2 Univariate and multivariate analysis of CSS in MBC patients

From: The clinical features and prognosis of patients with mucinous breast carcinoma compared with those with infiltrating ductal carcinoma: a population-based study

Features Univariate   Multivariate  
  HR (95%CI) P value HR (95%CI) P value
Sex
 Female 1  
 Male 1.834 (0.589–5.712) 0.295
Age
 < 60 years old 1   1  
 ≥ 60 years old 1.570 (1.256–1.962) < 0.001 1.596 (1.257–2.025) < 0.001
Race
 White 1   1  
 Black 1.718 (1.325–2.226) < 0.001 1.201 (0.918–1.572) 0.181
 Other 0.462 (0.302–0.706) < 0.001 0.433 (0.281–0.666) < 0.001
Marital status
 Married 1   1  
 Singled 2.448 (1.964–3.052) < 0.001 1.679 (1.333–2.114) < 0.001
Location
 Central portion of breast 1  
 Upper-inner quadrant 1.109 (0.691–1.781) 0.667
 Lower-inner quadrant 0.677 (0.389–1.178) 0.168
 Upper-outer quadrant 0.914 (0.615–1.358) 0.656
 Lower-outer quadrant 0.754 (0.436–1.304) 0.313
 Unspecific 3.152 (2.108–4.714) < 0.001
Grade
 I 1  
 II 1.310 (1.031–1.665) 0.027
 III 2.825 (1.931–4.133) < 0.001
 IV 2.564 (0.635–10.345) 0.186
SEER stage
 Local 1  
 Regional 4.427 (3.453–5.676) < 0.001
 Distant 48.018 (37.616–61.296) < 0.001
T-stage
 T1 1   1  
 T2 2.680 (2.070–3.469) < 0.001 1.971 (1.499–2.592) < 0.001
 T3 7.896 (5.726–10.889) < 0.001 3.321 (2.279–4.838) < 0.001
 T4 30.059 (22.181–40.735) < 0.001 4.382 (2.835–6.773) < 0.001
N-stage
 N0 1   1  
 N1 3.790 (2.881–4.985) < 0.001 1.642 (1.194–2.256) 0.002
 N2 6.135 (3.789–9.932) < 0.001 2.227 (1.316–3.769) 0.003
 N3 21.156 (14.901–30.036) < 0.001 1.678 (1.052–2.674) 0.030
M-stage
 M0 1   1  
 M1 36.539 (28.835–46.302) < 0.001 6.674 (4.771–9.336) < 0.001
TNM stage
 I 1  
 II 2.967 (2.246–3.920) < 0.001
 III 10.877 (7.662–15.440) < 0.001
 IV 75.573 (56.325–101.399) < 0.001
ER
 Negative 1   1  
 Positive 0.372 (0.234–0.591) < 0.001 0.559 (0.328–0.953) 0.033
PR
 Negative 1   1  
 Positive 0.498 (0.385–0.645) < 0.001 0.730 (0.545–0.97) 0.034
HER2
 Negative 1  
 Positive 0.833 (0.339–2.046) 0.691
Surgery
 No 1   1  
 Yes     
  Partial mastectomy 0.047 (0.037–0.061) < 0.001 0.334 (0.229–0.488) < 0.001
  Total mastectomya 0.095 (0.070–0.129) < 0.001 0.435 (0.299–0.631) < 0.001
  Radical mastectomyb 0.148 (0.113–0.195) < 0.001 0.470 (0.333–0.665) < 0.001
Radiotherapy
 No 1   1  
 Yes 0.316 (0.252–0.397) < 0.001 0.668 (0.508–0.880) 0.004
  1. aA simple mastectomy removes all breast tissue, the nipple, and areolar complex. An axillary dissection is not done
  2. bRadical mastectomy includes modified radical mastectomy, radical mastectomy NOS and extended radical mastectomy