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Table 5 Aesthetic outcome among patients with and without post-mastectomy radiotherapy

From: Reconstructive outcome analysis of the impact of neoadjuvant chemotherapy on immediate breast reconstruction: a retrospective cross-sectional study

Patients with PMRT

 

All (n = 32)

Implant-based reconstruction (n = 9)

Autologous reconstruction (n = 23)

Outcome

NACT (n = 21)

Non-NACT (n = 11)

P value

NACT (n = 6)

Non-NACT (n = 3)

P value

NACT (n = 15)

Non-NACT (n = 8)

P value

Breast shape of reconstructive site

3.7 ± 0.6

3.4 ± 0.9

0.328

3.2 ± 0.5

2.6 ± 1.0

0.251

3.8 ± 0.6

3.7 ± 0.6

0.601

Symmetry of infra-mammary fold

4.0 ± 0.6

3.6 ± 0.9

0.221

3.4 ± 0.5

2.4 ± 0.2

0.014*

4.2 ± 0.5

4.0 ± 0.6

0.483

Symmetry of breast volume

3.8 ± 0.5

3.4 ± 0.7

0.058

3.5 ± 0.7

2.6 ± 0.7

0.092

3.9 ± 0.5

3.6 ± 0.4

0.214

Symmetry of breast shape

3.5 ± 0.7

3.2 ± 0.8

0.180

3.1 ± 0.8

2.3 ± 0.7

0.177

3.7 ± 0.6

3.5 ± 0.6

0.426

Overall outcomes

3.6 ± 0.7

3.4 ± 0.7

0.540

3.1 ± 0.6

2.6 ± 0.8

0.381

3.8 ± 0.6

3.8 ± 0.4

0.772

Patients without PMRT

 

All (n = 155)

Implant-based reconstruction (n = 77)

Autologous reconstruction (n = 78)

Outcome

NACT (n = 14)

Non-NACT (n = 141)

P value

NACT (n = 9)

Non-NACT (n = 68)

P value

NACT (n = 5)

Non-NACT (n = 73)

P value

Breast shape of reconstructive site

3.5 ± 1.0

3.8 ± 0.7

0.129

3.1 ± 1.0

3.6 ± 0.8

0.089

4.3 ± 0.3

4.1 ± 0.5

0.323

Symmetry of infra-mammary fold

3.7 ± 0.9

4.0 ± 0.7

0.182

3.4 ± 0.9

3.8 ± 0.8

0.123

4.3 ± 0.4

4.2 ± 0.6

0.514

Symmetry of breast volume

3.7 ± 0.8

3.8 ± 0.7

0.380

3.4 ± 0.9

3.8 ± 0.8

0.160

4.2 ± 0.5

3.9 ± 0.6

0.273

Symmetry of breast shape

3.3 ± 0.9

3.7 ± 0.7

0.080

2.9 ± 0.9

3.5 ± 0.8

0.060

4.0 ± 0.5

3.9 ± 0.6

0.652

Overall outcomes

3.5 ± 1.0

3.8 ± 0.7

0.071

3.1 ± 1.0

3.6 ± 0.7

0.083

4.1 ± 0.6

4.1 ± 0.5

0.866

  1. PMRT postmastectomy radiotherapy, NACT neoadjuvant chemotherapy