Table 4 Showing hazard ratios for risk of progression to treatment, by different patient characteristics and clinical information at diagnosis (from multivariable cox regression)
Characteristics | Hazard Ratio (95% CI) |
|---|---|
Age at diagnosis (years) | |
≤ 65 | Reference |
> 65 | 0.89 (0.68–1.17) |
Year of diagnosis | |
≤ 2012 | Reference |
> 2012 | 0.72 (0.53–0.98) |
Ethnicity | |
Caucasian | Reference |
African/Afro-Caribbean | 0.86 (0.64–1.15) |
Other | 0.54 (0.22–1.31) |
PSA level (ng/mL) | |
< 5 | Reference |
5–10 | 1.04 (0.78–1.38) |
> 10 | 0.82 (0.53–1.29) |
Diagnostic Method | |
TP | Reference |
TRUS | 1.25 (0.85–1.83) |
Other | 0.91 (0.41–2.00) |
Diagnostic MRI | |
No MRI at diagnosis | Reference |
MRI at diagnosis | 0.75 (0.54–1.03) |
Gleason Score | |
≤ 3 + 3 | Reference |
3 + 4 | 2.41 (1.79–3.26) |
Number of cores taken | |
< 12 | Reference |
12–14 | 0.86 (0.49–1.49) |
15–24 | 0.96 (0.49–1.89) |
> 25 | 1.16 (0.58–2.34) |
Number of positive cores | |
1 | Reference |
2 | 1.44 (0.98–2.13) |
> 2 | 2.65 (1.94–3.62) |