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Table 4 The NRIs, IDIs, and C-indexes of the nomogram and AJCC staging system in OS prediction

From: A nomogram predicting overall survival in patients with non-metastatic pancreatic head adenocarcinoma after surgery: a population-based study

 

Training cohort

Validation cohort

Index

Estimate

95%CI

p value

Estimate

95%CI

p value

NRI (vs. the AJCC staging)

 For 12-month OS

0.305

0.248–0.357

 

0.212

0.155–0.332

 

 For 24-month OS

0.227

0.172–0.284

 

0.163

0.104–0.258

 

 For 36-month OS

0.057

0.003–0.108

 

0.087

0.024–0.232

 

 For 60-month OS

0.132

0.085–0.197

 

0.186

0.089–0.263

 

IDI (vs. the AJCC staging)

 For 12-month OS

0.05

 

p < 0.001

0.044

 

p < 0.001

 For 24-month OS

0.063

 

p < 0.001

0.059

 

p < 0.001

 For 36-month OS

0.056

 

p < 0.001

0.055

 

p < 0.001

 For 60-month OS

0.045

 

p < 0.001

0.046

 

p < 0.001

C-index

 The nomogram

0.676

0.665–0.687

 

0.667

0.649–0.684

 

 The AJCC staging

0.581

0.570–0.591

 

0.566

0.548–0.584

 

 Change

0.095

 

p < 0.001

0.101

 

p < 0.001

  1. AJCC: American Joint Committee on cancer; OS: overall survival; IDI: integrated discrimination improvement; NRI: net reclassification improvement; C-index: concordance index; CI: Confidence Interval
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BMC Cancer

ISSN: 1471-2407

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