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Table 4 Multivariable analyses for the combination of anatomical and morphological classification with survival in CCA patients using multiple cox regression

From: Survival after surgery among patients with cholangiocarcinoma in Northeast Thailand according to anatomical and morphological classification

Combination of anatomical and morphological classification Person-months IR per 100 Crude HR Adjusted **HR 95% CI P-value
 ICI 1885 1.9 Ref. Ref.   0.013
 ICM 4373 4.1 *2.03 *1.45 1.01–2.09  
 ICP 1161 2.3 1.18 0.96 0.58–1.59  
 ICMIX 294 3.1 1.39 0.84 0.40–1.77  
 PCM 990 4.7 *2.13 1.12 0.72–1.75  
 PCP 3074 3.8 *1.88 1.23 0.84–1.81  
 PCI 1397 1.9 0.96 0.84 0.51–1.40  
 PCMIX 605 3.5 1.55 0.80 0.46–1.39  
 DCM 675 3.0 1.44 0.74 0.42–1.29  
 DCP 821 2.6 1.35 0.91 0.52–1.58  
 DCI 369 2.4 1.30 1.05 0.50–2.21  
  1. CI Confidence interval, HR hazard ratio, Ref. reference group
  2. * P < 0.05
  3. ** Hazard ratio of anatomical classification adjusted for effects of stage of CCA, gender, age, O. viverrini infection, education levels, occupation, smoking cigarettes, alcohol drinking, and praziquantel treatment