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Fig. 5 | BMC Cancer

Fig. 5

From: Overexpression of TNFα induces senescence, autophagy and mitochondrial dysfunctions in melanoma cells

Fig. 5

Aldehyde dehydrogenase activity (ALDH) is reduced in TNFα overexpressing tumor cells. Proportion of ALDH positive (ALDH+) cells in engineered (a) melanoma (A375hTNFa) and (c, d) colorectal cancer (HT29hTNFa, HCT116hTNFa) cell lines decreases approx. by a half in comparison to parental cells; (b) M4Beu cells have low innate ALDH activity and increased proportion of ALDH+ cells. Flow cytometry, ALDEFLUOR assay

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BMC Cancer

ISSN: 1471-2407

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