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Fig. 3 | BMC Cancer

Fig. 3

From: Overexpression of TNFα induces senescence, autophagy and mitochondrial dysfunctions in melanoma cells

Fig. 3

Senescence induction in engineered melanoma cells overexpressing TNFα. Melanoma cells A375hTNFa (a, middle), M4BeuhTNFa (b, middle) entering senescence and senescent parental melanoma cells after treatment with recombinant TNFα (100 ng/ml) (a, b, left panel). In colorectal carcinoma cells HT29hTNFa and HCT116hTNFa (c) senescence is not induced. Senescent cells are blue enlarged cells; β-galactosidase staining on day 6 of cultivation; light microscope images, scale bar: 100 μm

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BMC Cancer

ISSN: 1471-2407

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