Table 6 Category of afatinib dose reduction
Variables | All patients | Afatinib 30 mg daily | Afatinib 40 mg daily | P value |
|---|---|---|---|---|
Dose reduction events | 39 (22%) | 8 (8%) | 31 (40%) | < 0.0001 |
Category of afatinib dose reduction | ||||
 No change | 140 (78%) | 94 (92%) | 46 (60%) |  |
 40 mg taper down to 30 mg | 22 (12%) |  | 22 (29%) |  |
 40 mg taper down to 20 mg | 7 (4%) |  | 7 (9%) |  |
 40 mg taper down to 0 mg | 2 (1%) |  | 2 (3%) |  |
 30 mg taper down to 20 mg | 1 (1%) | 1 (1%) |  |  |
 30 mg taper down to 15 mg | 5 (3%) | 5 (5%) |  |  |
 30 mg taper down to 0 mg | 2 (1%) | 2 (2%) |  |  |