Table 2 Treatment discontinuation and relative dose intensity
|  | Group A (n = 45) | Group B (n = 45) | P value |
|---|---|---|---|
Treatment discontinuation | 12 (26.7%) | 20 (44.4%) | 0.123 |
Reason for discontinuation | |||
 Toxicity or adverse event | 5 (11.1%) | 12 (26.7%) | 0.104 |
 Recurrence | 2 (4.4%) | 1 (2.2%) | 1.000 |
 2nd malignancy | 1 (2.2%) | 1 (2.2%) | 1.000 |
 Patient refusal | 3 (6.7%) | 3 (6.7%) | 1.000 |
 Investigator discision | 1 (2.2%) | 2 (2.2%) | 1.000 |
 Others | 0 (0%) | 1 (2.2%) | 1.000 |
Relative dose intensity at 1 year | |||
 Mean | 78.7% | 59.4% | 0.001 |
 Standard deviation | 25.6% | 32.1% |  |