MACE-Seq-based coding RNA and TrueQuant-based small RNA profile in breast cancer: tumor-suppressive miRNA-1275 identified as a novel marker

Table 1 Clinicopathological features of 22 cases with BC

Cases	Age	Tumor size	Stage	Lymph node metastasis	Lymphatic invasion	Venous invasion	E.R.	Pg.R.	Her2	Ki-67	Technique
Case1	74	4 cm	IIIA	Yes	1	1	Negative	Negative	Negative	60	MACE-seq & small RNA-seq
Case2	49	4 cm	IIIA	Yes	1	1	Negative	Negative	Negative	70	MACE-seq& small RNA-seq
Case3	35	4 cm	IIB	Yes	1	0	Negative	Negative	Positive	35	RT-PCR
Case4	64	4.5 cm	IIIA	Yes	1	0	Positive	Positive	Negative	5	RT-PCR
Case5	71	1.9 cm	I	No	0	0	Positive	Positive	Negative	Unavailable	RT-PCR
Case6	40	2.3 cm	IIB	Yes	1	0	Positive	Positive	Negative	4	RT-PCR
Case7	44	3.5 cm	IIIC	Yes	1	0	Positive	Positive	Negative	13	RT-PCR
Case8	53	2 cm	IIA	No	1	1	Positive	Negative	Positive	20–30	RT-PCR
Case9	46	1.8 cm	IIA	Yes	1	1	Positive	Negative	Positive	10	RT-PCR
Case10	33	1.4 cm	IIA	No	0	0	Positive	Positive	Positive	8	RT-PCR
Case11	49	5 cm	IIIC	Yes	1	0	Negative	Positive	Negative	13	RT-PCR
Case12	45	1.9 cm	IIIB	No	0	0	Negative	Negative	Negative	80–90	RT-PCR
Case13	64	1.5 cm	IIA	No	0	0	Negative	Negative	Negative	80–90	RT-PCR
Case14	49	1.7 cm	IIA	No	0	1	Negative	Negative	Negative	70–80	RT-PCR
Case15	35	1.3 cm	IIA	No	0	0	Negative	Negative	Negative	90	RT-PCR
Case16	52	3 cm	IIA	No	0	0	Negative	Negative	Negative	60	RT-PCR
Case17	18	2.5 cm	IIA	No	0	0	Positive	Negative	Negative	50	RT-PCR
Case18	63	1.5 cm	I	No	0	0	Negative	Negative	Positive	12	RT-PCR
Case19	19	2.5 cm	IIB	Yes	1	0	Positive	Positive	Negative	24	RT-PCR
Case20	30	1.3 cm	IIA	No	1	0	Positive	Positive	Negative	15–20	RT-PCR
Case21	45	1.5 cm	IIA	No	0	0	Positive	Positive	Negative	15–20	RT-PCR
Case22	44	6 cm	IIIC	Yes	0	0	Positive	Positive	Positive	7	RT-PCR

ISSN: 1471-2407