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Fig. 4 | BMC Cancer

Fig. 4

From: Whole genome sequencing in oncology: using scenario drafting to explore future developments

Fig. 4

Linear pools of individual PERT distributions for the overall likelihood of each scenario. The blue-shaded area under the curve represents the 80% highest density interval. The scenarios concerned: ‘innovation in WGS devices’ (scenario 1); ‘the discovery of a new actionable biomarker for immunotherapy’ (scenario 2); ‘the effect of centralizing WGS’ (scenario 3); ‘introducing WGS as a clinical diagnostic in oncology’ (scenario 4); ‘a new competing NGS panel ‘X” (scenario 5); ‘technical performance’ (scenario 6); ‘approval of new drugs for new actionable targets’ (scenario 7); ‘approval for off-label drug prescription’ (scenario 8); and ‘better treatment response to actionable targets found by WGS’ (scenario 9)

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