Fig. 6From: Transcriptome analysis of potential candidate genes and molecular pathways in colitis-associated colorectal cancer of Mkp-1-deficient micea PPI network of common DEGs using STRING. The protein–protein interaction (PPI) network constructed using the differentially expressed genes common to both adenoma KO and carcinoma KO. This network contained 194 nodes and 132 interaction pairs Tnf, Postn, Itga8, Acta2, Tagln, Cxcl1, Ogn, Eno3, and Nr5a2 had high degrees. b Heatmap for hub genes showing that most of them are down-regulated in KO miceBack to article page