Courses | PDL Group (Median) | p-value* | PGL Group (Median) | p-value* | p-value** | |||||
---|---|---|---|---|---|---|---|---|---|---|
D0 | D7 | D15 | D0 | D7 | D15 | |||||
1 | WBC | 8900 | 4100 | 5850 | < 0.001 | 9550 | 3850 | 5750 | < 0.001 | 0.295 |
Hb | 13.20 | 13.00 | 13.00 | < 0.001 | 12.80 | 12.35 | 12.25 | < 0.001 | 0.159 | |
Plt | 280,000 | 124,000 | 173,000 | < 0.001 | 248,500 | 124,000 | 168,000 | < 0.001 | 0.416 | |
Neut | 75 | 50 | 85 | < 0.001 | 70 | 50 | 85 | < 0.001 | 0.312 | |
Lymph | 25 | 50 | 15 | < 0.001 | 27 | 50 | 15 | < 0.001 | 0.130 | |
ANC | 6545 | 2050 | 5025 | < 0.001 | 6830 | 1660 | 4600 | < 0.001 | 0.327 | |
2 | WBC | 5850 | 3100 | 4400 | < 0.001 | 5750 | 3000 | 4500 | < 0.001 | 0.866 |
Hb | 13.00 | 13.00 | 12.90 | < 0.001 | 12.25 | 12.20 | 12.20 | < 0.001 | 0.307 | |
Plt | 173,000 | 111,000 | 156,000 | < 0.001 | 168,000 | 107,000 | 156,000 | < 0.001 | 0.468 | |
Neut | 85 | 50 | 85 | < 0.001 | 85 | 50 | 86 | < 0.001 | 0.504 | |
Lymph | 15 | 50 | 13 | < 0.001 | 15 | 50 | 14 | < 0.001 | 0.243 | |
ANC | 5025 | 1575 | 3838 | < 0.001 | 4600 | 1400 | 3895 | < 0.001 | 0.950 | |
3 | WBC | 4400 | 2450 | 3950 | < 0.001 | 4500 | 2500 | 3950 | < 0.001 | 0.820 |
Hb | 12.90 | 12.90 | 12.30 | < 0.001 | 12.20 | 12.00 | 12.00 | < 0.001 | 0.107 | |
Plt | 156,000 | 101,000 | 139,000 | < 0.001 | 156,000 | 100,000 | 146,000 | < 0.001 | 0.302 | |
Neut | 85 | 50 | 90 | < 0.001 | 86 | 50 | 90 | < 0.001 | 0.023 | |
Lymph | 15 | 50 | 10 | < 0.001 | 14 | 50 | 10 | < 0.001 | 0.006 | |
ANC | 3838 | 1305 | 1975 | < 0.001 | 3895 | 1200 | 1900 | < 0.001 | 0.229 | |
4 | WBC | 3950 | 1900 | 3100 | < 0.001 | 3950 | 2100 | 3400 | < 0.001 | 0.443 |
Hb | 12.30 | 12.05 | 12.05 | < 0.001 | 12.00 | 12.00 | 12.00 | < 0.001 | 0.473 | |
Plt | 139,000 | 92,500 | 128,500 | < 0.001 | 146,000 | 98,000 | 132,000 | < 0.001 | 0.969 | |
Neut | 90 | 50 | 90 | < 0.001 | 90 | 50 | 90 | < 0.001 | 0.317 | |
Lymph | 10 | 50 | 11 | < 0.001 | 10 | 50 | 10 | < 0.001 | 0.143 | |
ANC | 1975 | 955 | 2738 | < 0.001 | 1900 | 1020 | 2872 | < 0.001 | 0.548 | |
5 | WBC | 3100 | 2500 | 4500 | < 0.001 | 3400 | 2500 | 4900 | < 0.001 | 0.341 |
Hb | 12.05 | 12.00 | 12.00 | 0.095 | 12.00 | 12.00 | 11.50 | < 0.001 | 0.237 | |
Plt | 128,500 | 100,000 | 151,000 | < 0.001 | 132,000 | 102,000 | 159,000 | < 0.001 | 0.974 | |
Neut | 90 | 50 | 90 | < 0.001 | 90 | 50 | 90 | < 0.001 | 0.413 | |
Lymph | 11 | 50 | 10 | < 0.001 | 10 | 50 | 10 | < 0.001 | 0.590 | |
ANC | 2738 | 1350 | 3895 | < 0.001 | 2872 | 1250 | 4410 | < 0.001 | 0.289 | |
6 | WBC | 4500 | 3200 | 6750 | < 0.001 | 4900 | 3450 | 6800 | < 0.001 | 0.581 |
Hb | 12.00 | 12.00 | 12.00 | 0.001 | 11.50 | 11.40 | 11.30 | < 0.001 | 0.206 | |
Plt | 151,000 | 111,500 | 159,500 | < 0.001 | 159,000 | 110,000 | 174,000 | < 0.001 | 0.919 | |
Neut | 90 | 50 | 90 | < 0.001 | 90 | 50 | 90 | < 0.001 | 0.663 | |
Lymph | 10 | 50 | 10 | < 0.001 | 10 | 50 | 10 | < 0.001 | 0.743 | |
ANC | 3895 | 1725 | 5948 | < 0.001 | 4410 | 1900 | 6120 | < 0.001 | 0.543 | |
7 | WBC | 6750 | 4200 | 8400 | < 0.001 | 6800 | 4600 | 9100 | < 0.001 | 0.050 |
Hb | 12.00 | 11.90 | 11.50 | < 0.001 | 11.30 | 11.30 | 11.30 | 0.002 | 0.342 | |
Plt | 159,500 | 121,000 | 170,500 | < 0.001 | 174,000 | 124,000 | 186,000 | < 0.001 | 0.559 | |
Neut | 90 | 50 | 90 | < 0.001 | 90 | 50 | 90 | < 0.001 | 0.306 | |
Lymph | 10 | 50 | 10 | < 0.001 | 10 | 50 | 10 | < 0.001 | 0.898 | |
ANC | 5948 | 2100 | 7560 | < 0.001 | 6120 | 2300 | 8330 | < 0.001 | 0.146 | |
8 | WBC | 8400 | 4950 | 10,000 | < 0.001 | 9100 | 5100 | 10,550 | < 0.001 | 0.395 |
Hb | 11.50 | 11.35 | 11.35 | < 0.001 | 11.30 | 11.25 | 11.25 | < 0.001 | 0.528 | |
Plt | 170,500 | 124,000 | 186,500 | < 0.001 | 186,000 | 124,000 | 194,500 | < 0.001 | 0.637 | |
Neut | 90 | 50 | 90 | < 0.001 | 90 | 50 | 90 | < 0.001 | 0.781 | |
Lymph | 10 | 50 | 10 | < 0.001 | 10 | 50 | 10 | < 0.001 | 0.838 | |
ANC | 7560 | 2525 | 9000 | < 0.001 | 8330 | 2575 | 9601 | < 0.001 | 0.434 |