From: Extra-abdominal desmoid tumor fibromatosis: a multicenter EMSOS study
Group | I: Chemotherapy (#17) | II: Hormone therapy (#15) | III: NSAIDS (#16) | IV: Radiotherapy (#13) | V: Surgery (#257) | VI: Active surveillance (#70) | Overall (#388) |
---|---|---|---|---|---|---|---|
Age (years) | |||||||
Mean | 30,8 | 39,7 | 38,1 | 45,8 | 36,6 | 40,6 | 37,5 |
Min | 10 | 15 | 11 | 15 | 3 | 10 | 3 |
Max | 53 | 74 | 63 | 69 | 81 | 85 | 85 |
Gender | |||||||
Female | 10 | 11 | 8 | 7 | 158 | 46 | 240 |
Male | 7 | 4 | 8 | 6 | 99 | 24 | 148 |
Presentation | |||||||
Primary | 11 | 10 | 14 | 11 | 193 | 57 | 296 |
Recurrent | 6 | 5 | 2 | 2 | 62 | 13 | 90 |
Diagnosis delay | |||||||
Mean | 20,9 | 15,8 | 15,2 | 13,5 | 13,1 | 13,5 | 13,8 |
Min | 1 | 1 | 2 | 1 | 0 | 0 | 0 |
Max | 72 | 72 | 53 | 60 | 120 | 120 | 120 |
Biopsy | |||||||
Incisional | 15 | 10 | 3 | 1 | 134 | 27 | 190 |
Needle | 2 | 5 | 13 | 11 | 98 | 41 | 170 |
Beta catenin | |||||||
Not invastigated | 13 | 9 | 5 | 2 | 179 | 39 | 247 |
Negative | 1 | 7 | 3 | 11 | |||
Positive | 4 | 6 | 10 | 10 | 57 | 25 | 112 |
Location | |||||||
Arm | 2 | 1 | 25 | 9 | 37 | ||
Foot | 1 | 8 | 2 | 11 | |||
Forearm | 2 | 12 | 4 | 18 | |||
Hand/wrist | 3 | 3 | |||||
Leg | 2 | 2 | 2 | 3 | 23 | 3 | 35 |
Pelvic girdle | 5 | 5 | 4 | 41 | 17 | 72 | |
Shoulder girdle | 3 | 5 | 7 | 7 | 78 | 19 | 119 |
Thigh | 4 | 1 | 3 | 53 | 12 | 73 | |
Size | |||||||
< 5 cm | 3 | 3 | 5 | 78 | 24 | 113 | |
5–10 cm | 7 | 9 | 5 | 9 | 118 | 32 | 180 |
> 10 cm | 7 | 3 | 6 | 4 | 56 | 13 | 89 |
Location | |||||||
Deep | 17 | 15 | 15 | 12 | 208 | 57 | 324 |
Extra-fascial | 1 | 1 | 38 | 11 | 51 | ||
Nerve Involvement | |||||||
Present | 4 | 3 | 3 | 8 | 40 | 9 | 67 |
Neurologic symptoms | |||||||
Present | 3 | 4 | 2 | 4 | 28 | 4 | 45 |
Previous local events | |||||||
Surgery | 6 | 5 | 1 | 1 | 38 | 17 | 68 |
Trauma | 2 | 1 | 3 | 1 | 22 | 4 | 33 |
Hormonal status (females only) | |||||||
Menopause | 1 | 3 | 22 | 7 | 33 | ||
Pregnancy | 1 | 2 | 1 | 4 | |||
Recent pregnancy | 1 | 1 | 5 | 4 | 11 | ||
Pain | |||||||
Absent | 3 | 3 | 4 | 3 | 97 | 25 | 135 |
Mild | 9 | 4 | 5 | 7 | 74 | 34 | 133 |
Moderate | 4 | 7 | 6 | 45 | 9 | 71 | |
Severe | 1 | 1 | 1 | 3 | 11 | 1 | 18 |