Fig. 5

DNA damage index. DNA damage quantification by alkaline comet assay was performed immediately after 12 h of treatment with 5-FU and/or Olaparib in HT29 (a) and HCT116 (b) and cell lines (n = 3). Untreated cells were used as negative control. *p < 0.05, **p < 0.01, ***p < 0.001 and ****p < 0.0001 above error bars vs. control