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Fig. 1 | BMC Cancer

Fig. 1

From: MKL1 regulates hepatocellular carcinoma cell proliferation, migration and apoptosis via the COMPASS complex and NF-κB signaling

Fig. 1

Elevated MKL1 gene expression in HCC tissues and cell lines. a-b The expressional differences of MKL1 gene between normal liver tissues and human hepatocellular carcinoma tissues. MKL1 gene expression was assessed by searching the Oncomine database. c The expression of MKL1 genes in normal liver tissues and liver tissues collected from patients with liver cirrhosis, hepatocellular carcinoma and liver cell dysplasia. MKL1 gene expression levels were evaluated using the Oncomine database. d. The correlation of MKL1 gene expression and survival of patients with HCC. The survivals of HCC patients with low or high expression of MKL1 gene were shown in blue and red lines respectively. e The MKL1 mRNA levels in hepatocellular carcinoma cell lines. MLK1 mRNA levels were detected by quantitative RT-PCR method. f Alterations of the MKL1 protein abundances in hepatocellular carcinoma cell lines. Western blotting was performed to detect MKL1 protein levels using GAPDH as the internal standard. Full-length blots/gels are presented in Additional files 1A. *P < 0.05; **P < 0.01

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