Table 1 Patient characteristics
Variables | n 365 (100%) |
|---|---|
Age at diagnosis; years | |
Mean | 62 |
Range | 25–80 |
< 63 | 189 (51.8%) |
≥ 63 | 176 (48.2%) |
> 70 | 56 (15.3%) |
Gender | |
Female | 176 (48.2%) |
Male | 189 (51.8%) |
Body mass index (kg/m2) | |
Median | 26.4 |
Range | 15 (6–44) |
≤ 18,5 | 13 (3.6%) |
18,5-24,9 | 128 (35.1%) |
≥ 25,0 | 224 (61.4%) |
Diabetes mellitus | |
No | 325 (89%) |
Yes | 40 (11%) |
Histology | |
Adenocarcinoma not otherwise specified (NOS) | 304 (83.3%) |
Mucinous adenocarcinoma | 54 (14.8%) |
Adenocarcinoma of cylindrical cells | 2 (0.5%) |
Signet ring adenocarcinoma | 2 (0.5%) |
Adenosquamous carcinoma | 1 (0.3%) |
Undifferentiated carcinoma | 2 (0.5%) |
Histopathology grade (G) | |
G1 (well differentiated) | 33 (9.0%) |
G2 (moderate differentiated) | 279 (76.4%) |
G3 (poor differentiated) | 52 (14.2%) |
No data | 1 (0.3%) |
Primary tumor classification (pT) | |
1 | 3 (0.8%) |
2 | 47 (12.9%) |
3 | 249 (68.2%) |
4a | 48 (13.2%) |
4b | 18 (4.9%) |
Regional lymph nodes classification (pN) | |
1a | 106 (29.0%) |
1b | 119 (32.6%) |
1c | 1 (0.3%) |
1 | 1 (0.3%) |
2a | 80 (21.9%) |
2b | 58 (15.9%) |
Number of harvested lymph nodes | |
< 12 | 196 (53.7%) |
≥ 12 | 165 (45.2%) |
No data | 4 (1.1%) |
Primary tumor location | |
Ceacum | 64 (17.5%) |
Ascending colon | 49 (13.4%) |
Hepatic flexure | 28 (7.7%) |
Transverse colon | 20 (5.5%) |
Splenic flexure | 22 (6.0%) |
Descending colon | 14 (3.8%) |
Sigmoid colon | 168 (46.1%) |
Primary tumor location | |
Right colon | 161 (44.1%) |
Left colon | 203 (55.6%) |
No data | 1 (0.3%) |
Surgery | |
Right hemicolectomy | 116 (31.8%) |
Right hemicolectomy extended | 36 (9.9%) |
Left hemicolectomy | 45 (12.3%) |
Sigmoidectomy | 167 (45.8%) |
Transversectomy | 1 (0.3%) |
Adjuvant chemotherapy | |
FOLFOX-4 | 336 (92%) |
CAPOX (XELOX) | 29 (8%) |
CEA concentration before surgery; ng/ml | |
< 5 | 96 (26.3%) |
≥ 5 | 28 (7.7%) |
No data | 241 (66.0%) |
CEA concentration after surgery; ng/ml | |
< 5 | 292 (80.0%) |
≥ 5 | 33 (9.0%) |
No data | 40 (11.0%) |