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Table 2 Statistical association of TACSTD2 methylation and clinicopathological characteristics in logistic regression analyses

From: DNA methylation of tumor associated calcium signal transducer 2 (TACSTD2) loci shows association with clinically aggressive renal cell cancers

TACSTD2 methylation

OR (95% CI)

p-value

Metastasis (M0 vs. M1)

1.18 (1.05–1.35)

0.008

Lymph node status (N0 vs. N1)

1.21 (1.03–1.43)

0.021

Tumor stage (low vs. high T*)

1.18 (1.06–1.31)

0.003

Differentiation (low vs. high G**)

1.16 (1.01–1.34)

0.033

State of Disease (loc vs. adv***)

1.20 (1.08–1.34)

< 0.001

  1. Abbreviations: vs versus
  2. OR odds ratio; 95% CI 95% confidence interval
  3. *Low defined as T1 and T2; high defined as T3 and T4
  4. ** Low defined as G1, G2; high defined as ≥G3
  5. ***Localized disease (loc) defined as pT ≤ 2, N0, M0; advanced disease (adv) defined as pT ≥ 3 and/or N1, M1