Skip to main content

Table 1 Characteristics of the studies examined in the meta-analysis

From: The prognostic significance of survivin expression in patients with HNSCC: a systematic review and meta-analysis

Author Year Country Ethnicity Cancer type Sample size Age Follow-up (month) Survival analysis Method Cut-off value HR NOS/REMARK score
Elhadj [17] 2019 Tunisia Non-Asian LSCC 70 63 (45–88) NR OS, DFS IHC 5% Reported 7/12
Erpolat [18] 2012 Turkey Non-Asian HNSCC 58 56.7 (35–80) 56.5 (38.7–112.5) OS IHC 5% Reported 7/11
Fiedler [19] 2018 Germany Non-Asian HNSCC 139 60.5 (43.4–83.6) 17.4 (0–120.9) OS,DSS IHC median value Reported 6/14
Jin [20] 2019 China Asian NPC 164 45.0 (24–70) 49.2 (9–60) OS,DMFS, LRFS,DFS IHC, RT-PCR 0% Reported 6/13
Li [21] 2008 China Asian NPC 280 46 (14–86) NR OS IHC 5% Reported 7/11
Li [22] 2011 China Asian LSCC 86 51 (37–84) NR OS IHC 0% Reported 7/12
Lin [23] 2005 China Asian OSCC 96 NR NR OS IHC 25% Reported 6/12
Muzio [24] 2005 Italy Non-Asian OSCC 78 66.5 (18–87) 72 DSS IHC 75% Reported 7/12
Preuss [25] 2008 Australia Non-Asian OSCC 106 57 (34–82) 20.3 (0.33–79.8) DFS IHC 5% Reported 7/13
Tastekin [26] 2017 Turkey Non-Asian OSCC 46 59.48 (31–91) NR OS IHC 13.00% Reported 6/11
Wang [27] 2011 China Asian NPC 1268 46 (15–90) 69 (1–20) DSS IHC median value Reported 7/13
Xiang [28] 2006 China Asian NPC 80 NR 60 OS, DFS IHC 25% Reported 7/13
Yip [29] 2006 Canada Non-Asian NPC 198 NR 136.8 OS IHC 5% Reported 8/15
Zhao [30] 2008 China Asian LSCC 146 54.6 (42–76) 41.4 (36–72) DFS IHC 5% Reported 7/14
Dong [31] 2002 Japan Asian LSCC 102 63.49 (38–89) NR OS,DFS IHC 5% Reported 7/13
Kim [32] 2005 South Korea Asian OSCC 113 58 (18–78) NR OS RT-PCR 50% Estimated 6/12
Zhang [33] 2013 China Asian OSCC 110 58 (37–78) > 60 OS IHC median value Estimated 7/13
Farnebo [34] 2013 Sweden Non-Asian HNSCC 40 68 30 OS IHC 0% Estimated 6/11
Freier [35] 2007 Germany Non-Asian OSCC 296 60 (16–92) 34 (0–147) OS IHC 10% Estimated 7/13
Hansson [36] 2017 Sweden Non-Asian LSCC 149 NR 67 (9–163) DFS IHC 10% Estimated 7/11
Munscher [37] 2019 Germany Non-Asian HNSCC 452 NR 41.3 (1–306) OS,RFS IHC 50% Estimated 7/11
Pickhard [38] 2014 Germany Non-Asian HNSCC 180 53 (35–72) 60–162 OS IHC 10% Estimated 6/11
Su [39] 2010 China Asian OSCC 78 NR NR OS IHC,RT-PCR median value Estimated 6/11
Troiano [40] 2018 Italy Non-Asian OSCC 342 NR NR OS IHC 60% Estimated 7/11
Pizem [41] 2004 Slovenia Non-Asian LSCC 68 59.2 (37–78) NR OS IHC 50% Estimated 6/12
Marioni [42] 2013 Italy Non-Asian LSCC 33 NR 43 DFS IHC 10.00% Estimated 6/11
Marioni [43] 2017 Italy Non-Asian LSCC 75 63.6 67.3 DFS IHC 6% Estimated 7/13
Kim [44] 2010 South Korea Asian OSCC 38 58.5 (40–75) NR OS IHC 20% Estimated 6/11