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Table 1 Changes in levels of apoptosis related protein in leukemic cell lines

From: Intrinsic and extrinsic apoptosis responses in leukaemia cells following daunorubicin treatment

  MOLT-4 CCRF-CEM SUP-B15
Apoptotic protein DNR 4 h Recovery Medium 12 h DNR 4 h Recovery Medium 12 h DNR 4 h Recovery Medium 12 h
Intrinsic Pathway
 p53
 Bad
 Bax
 Bcl-2
 Bcl-w
 cytC
 SMAC
Extrinsic Pathway
 Fas
 FasL
 sTNF-R1
 TRAIL-3
 TNF-α
 CD40
 Casp-8
 Casp-3
  1. MOLT-4, CCRF-CEM, and SUP-B15 treated with 10 μM daunorubicin for 4 h and allowed 12 h recovery in drug-free medium