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Fig. 3 | BMC Cancer

Fig. 3

From: COXIBs and 2,5-dimethylcelecoxib counteract the hyperactivated Wnt/β-catenin pathway and COX-2/PGE2/EP4 signaling in glioblastoma cells

Fig. 3

The effect of PKF118–310, COXIBs, and 2,5-DMC on the expression of β-catenin (CTNNB1) and its target genes after 48 h of treatment of A-172, T98G, and U-138 MG cell lines. The concentration of compounds used in this assay provided at least 70% of cell viability. Means ± SEM from two separate experiments with three replicates in each are presented. The values were calculated as mRNA level in comparison with control cells treated with DMSO (expression equals 1). The asterisk (*) above the bar denotes a statistically significant difference from the control group, p < 0.05

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