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Table 1 Correlations of major clinical/pathological factors and recurrence after CCRT and adjacent surgery in stage IIB–III cervical cancer

From: Clinical outcomes observation in stage IIB–IIIB cervical cancer treated by adjuvant surgery following concurrent chemoradiotherapy

Factors

 

Number (%)

Recurrence

χ2

p

No

Yes

Age

<50

28(57.1)

50

3

5. 168

0.023*

≥50

21(42.9)

13

8

  

HPV infection

No

31(63.3)

25

6

0.464

0.496

Yes

18(36.7)

13

5

  

Tumor diameters

≤4 cm

20(40.8)

14

6

1.107

0.293

>4 cm

29(59.2)

24

5

  

Pathological differentiation

High

7(14.3)

5

2

0.979

0.613

Moderatly

33(67.3)

25

8

  

Low

9(18.4)

8

1

  

Pathologic subtypes

Adenocarcinoma/mixed subtypes

7(14.3)

4

3

1.954

0.162

SCC

42(85.7)

34

8

  

FIGO stage

IIB

41(83.7)

32

9

0.657

0.720

IIIA

1(2.0)

1

0

  

IIIB

7(14.3)

5

2

  

Microscopic residual

No

27(55.1)

20

7

8.920

0.012*

Disease invading less than 50% of the myometrium

13(26.5)

13

0

8.920

0.012*

Disease invading more than 50% of the myometrium

9(18.4)

5

4

  
  1. CCRT concurrent chemoradiotherapy, HPV human papillomavirus, FIGO International Federation of Gynecology and Obstetrics, SCC squamous cell carcinoma, *P<0.05