Table 1 Patient characteristics
Characteristics | Â | Â | P-value |
|---|---|---|---|
|  | KRAS-wt (n = 63) n (%) | KRAS-mut (n = 38) n (%) |  |
Sex, male/female | 36/27 (57.1/42.9) | 22/16 (57.9/42.1) | 1.000 |
Median age (range) (years) | 66 (33–83) | 69 (35–82) | 0.821 |
Primary tumor | |||
 Right-sided/Left-sided/rectum | 11/31/21 (17.5/49.2/33.3) | 7/18/13 (18.4/47.4/34.2) | 0.983 |
 pT1–3 / T4 | 36/27 (57.1/42.9) | 23/15 (60.5/39.5) | 0.738 |
 Node positive / node negative | 48/15 (76.2/23.8) | 30/8 (78.9/21.1) | 0.811 |
Initial liver metastases | |||
 Synchronous / metachronous diagnosis | 34/29 (54.0/46.0) | 22/16 (57.9/42.1) | 0.837 |
Unilobar / bilobar | 36/27 (57.1/42.9) | 18/20 (47.4/52.6) | 0.412 |
Mean number of tumors, (range) | 3.7 (1–26) | 3.6 (1–19) | 0.910 |
Solitary / multiple metastases | 23/40 (36.5/63.5) | 12/26 (31.6/68.4) | 0.670 |
Largest tumor’s mean size, cm, | 3.8 (0.5–13) | 3.5 (0.8–10) | 0.531 |
Serum carcinoembryonic antigen (ng/mL), < 5 / ≥5 | 17/46 (27.0/73.0) | 13/25 (34.2/65.8) | 0.503 |
Hepatectomy, minor/major | 43/20 (68.3/31.8) | 27/11 (71.1/28.9) | 0.827 |
Surgical margin, R0/R1 | 44/19 (69.8/30.2) | 26/12 (68.4/31.6) | 1.000 |
Preoperative chemotherapy, yes/no | 37/26 (58.7/41.3) | 23/15 (60.5/39.5) | 1.000 |
Adjuvant chemotherapy, yes/no | 41/22 (65.1/34.9) | 25/13 (65.8/34.2) | 1.000 |