Expression and functional characterization of INPP4B in gallbladder cancer patients and gallbladder cancer cells

BMC Cancer

Table 1 Relationship between INPP4B expression and clinicopathological variables (n = 127)

Clinicopathological variables	Total	INPP4B expression		p value
Clinicopathological variables	Total	positive (58)	negative (69)	p value
Sex				0.862
Male	36	16	20
Female	91	42	49
Age (y)				0.984
< 68	59	27	32
≥ 68	68	31	37
Tumor size (cm)				0.116
< 2	67	35	32
≥ 2	60	23	37
Differentiation				0.026
High/moderate	81	43	38
Low/undifferentiated	46	15	31
Depth of invasion				0.754
T1/T2	39	17	22
T3/T4	88	41	47
Lymph node metastasis				0.405
Yes	51	21	30
No	76	37	39
TNM				0.735
I/II	83	37	46
III/IV	44	21	23
Gallstones				0.321
Yes	84	41	43
No	43	17	26
AFP (ug/L)				0.999
< 20	122	56	66
≥ 20	5	2	3
CEA (ng/ML)				0.771
< 5	100	45	55
≥ 5	27	13	14
CA199 (U/ML)				0.735
< 37	83	37	46
≥ 37	44	21	23

TNM tumor-node-metastasis, AFP alpha fetoprotein, CEA carcino-embryonic antigen, CA199 carbohydrate antigen 199
p < 0.05 was defined statistically significant

ISSN: 1471-2407