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Table 6 Multivariate Cox proportional hazard analysis for OS in SqCC

From: Role of Synaptophysin, Chromogranin and CD56 in adenocarcinoma and squamous cell carcinoma of the lung lacking morphological features of neuroendocrine differentiation: a retrospective large-scale study on 1170 tissue samples

Variable HR (CI95) p value
Stage II 1.657 (1.135–2.419) 0.009a
Stage III 2.889 (1.954–4.274) < 0.001a
Stage IV 4.205 (1.298–13.624) 0.017a
Age (> 59 versus < 59 years) 1.282 (0.900–1.826) 0.168
Gender (female versus male) 0.790 (0.504–1.239) 0.305
Neuroendocrine marker (positivity versus negativity) 0.697 (0.436–1.113) 0.131
  1. n = 533
  2. OS overall survival
  3. aas compared to Stage I